Results 81 to 90 of about 676,913 (315)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

PSYCHIATRIC WARD IN GENERAL HOSPITAL: PROFESSIONALS VIEW WHO WORKS IN GENERAL HOSPITAL [PDF]

open access: yesRevista Eletrônica de Enfermagem, 2003
The proposal of this study was the one of looking for the professionals of health that act in generalhospital, the perception and the acceptance of the same ones on the possible implantation of psychiatric beds inthe institution close to in that act. The
Jacó Fernando Schneider   +1 more
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

COMPEREHENSIVE TECHNICAL STUDIES OF FLOOD CONTROL OVER SOLO CITY AREA (CASE STUDY IN DEMANGAN BARRAGE)

open access: yesJournal of the Civil Engineering Forum, 2013
City of Surakarta, known as Solo City is one of cities in Central Java Province traversed by Bengawan Solo River. Heavy rainfall in upstream area of Bengawan Solo River causes increase in high water level at downstream. Bengawan Solo River will be higher
Ali Trusharyanto   +2 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

A Comparative Study of the General Health among Staff Nurses with Fixed or Rotating Working Shift

open access: yesنشریه پرستاری ایران, 2007
Introduction and Aim: Long time working shifts and its related tiredness threatens the health of staff nurses in various dimensions. If nurses don’t experience a good general health, they would not be able to deliver good patient care.
M .A. Soleimany   +3 more
doaj  

Hydrology and Hydraulic Analysis of Nasiri Flash Flood Disaster Event on the 1st August 2012

open access: yesJournal of the Civil Engineering Forum, 2018
Nasiri lays in the Luhu village, Huamual district, West Seram Regency, Maluku province. Nasiri experienced in flash flood on August 1st, 2012 which had never happened before. There was no rainfall station and water level recorder at that time.
Imam Syarif Hidayatulloh   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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