Results 61 to 70 of about 36,027 (210)

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Aspects of elliptic hypergeometric functions [PDF]

, 2013
General elliptic hypergeometric functions are defined by elliptic hypergeometric integrals. They comprise the elliptic beta integral, elliptic analogues of the Euler-Gauss hypergeometric function and Selberg integral, as well as elliptic extensions of ...
Spiridonov, V. P.
core  

Generalized photon-added associated hypergeometric coherent states: characterization and relevant properties

, 2017
This paper presents the construction of a new set of generalized photon-added coherent states related to associated hypergeometric functions introduced in our previous work (Hounkonnou M N and Sodoga K, 2005, J. Phys. A: Math. Gen 38, 7851). These states
Aremua, I., Hounkonnou, M. N., Sodoga, K.   +2 more
core   +1 more source

Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis

Advanced Science, EarlyView.
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan, Yunping Chen, Wei Zhou, Yanghong Xu, Junran Huang, Yi Chen, Jizhou Meng, Guoxin Yao, Wenchao Huang   +8 more
wiley   +1 more source

Feynman integral in $\mathbb R^1\oplus\mathbb R^m$ and complex expansion of $_2F_1$

, 2016
Closed form expressions are proposed for the Feynman integral $$ I_{D, m}(p,q) = \int\frac{d^my}{(2\pi)^m}\int\frac{d^Dx}{(2\pi)^D} \frac1{(x-p/2)^2+(y-q/2)^4} \frac1{(x+p/2)^2+(y+q/2)^4} $$ over $d=D+m$ dimensional space with $(x,y),\,(p,q)\in
Pogány, Tibor K., Shpot, Mykola A.
core   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

Advanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, Zhilong Chen, Lingzhao Fang, Yunxiang Zhao, Yuwen Liu   +13 more
wiley   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

A Class of Extended Fractional Derivative Operators and Associated Generating Relations Involving Hypergeometric Functions

Axioms, 2012
Recently, an extended operator of fractional derivative related to a generalized Beta function was used in order to obtain some generating relations involving the extended hypergeometric functions [1].
H. M. Srivastava, Rakesh K. Parmar, Purnima Chopra   +2 more
doaj   +1 more source

Expansions of the solutions of the general Heun equation governed by two-term recurrence relations for coefficients

, 2018
We examine the expansions of the solutions of the general Heun equation in terms of the Gauss hypergeometric functions. We present several expansions using functions, the forms of which differ from those applied before.
Ishkhanyan, A. M., Ishkhanyan, T. A., Shahverdyan, T. A.   +2 more
core   +2 more sources