Results 81 to 90 of about 1,017,855 (122)

Sirolimus treatment of generalized lymphatic anomaly with a set of congenital defects

Polish Archives of Internal Medicine
Piotr, Piekarczyk, Katarzyna, Błasińska, Mateusz, Polaczek, Magdalena, Bilny-Paluch, Elżbieta, Radzikowska   +4 more
openaire   +2 more sources

Efficacy of Systemic Sirolimus in the Treatment of Generalized Lymphatic Anomaly and Gorham–Stout Disease [PDF]

Pediatric Blood and Cancer, 2019
AbstractBackgroundGeneralized lymphatic anomaly (GLA) and Gorham–Stout disease (GSD) are rare complicated lymphatic malformations that occur in multiple body sites and are associated with significant morbidity and mortality. Treatment options have been limited, and conventional medical therapies have been generally ineffective.
Julia L Glade Bender, Anna Synakiewicz, Ilona J. Frieden   +2 more
exaly   +7 more sources

A Case of Generalized Lymphatic Anomaly Causing Skull-Base Leakage and Bacterial Meningitis [PDF]

Brain and Development, 2017
Generalized lymphatic anomaly is a multifocal lymphatic malformation that affects the skin, thoracic viscera, and bones. A 3year-old Japanese boy presented with right facial palsy due to cystic tumors in the ipsilateral petrous bone. Pericardial effusion had been found incidentally and generalized lymphatic anomaly had been diagnosed by pericardial ...
Kenichi Suga, Miki Inoue, Kazuhiro Mori
exaly   +4 more sources

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Case 311: Generalized Lymphatic Anomaly

Radiology, 2023
A 14-year-old boy presented with asthenia, low back pain, and abdominal distention. The onset of symptoms was slow and progressive over a few months. The patient had no contributing past medical history. At physical examination, all vital signs were normal.
Pablo Ramallo, Sara Blanque, Luis Méndez Uriburu, Jorge Ahualli, Alfonso Méndez, Marco Méndez   +5 more
openaire   +2 more sources

Complex Lymphatic Anomalies: Report on a Patient Registry Using the Latest Diagnostic Guidelines [PDF]

Lymphatic Research and Biology, 2023
Objective: Generalized lymphatic anomaly (GLA), Gorham-Stout disease (GSD), kaposiform lymphangiomatosis (KLA), and central conducting lymphatic anomaly (CCLA) are rare, multisystem lymphatic disorders, referred to as complex lymphatic anomalies (CLAs ...
Iris Baumgartner, Friedrich G Kapp, Charlotte Niemeyer   +2 more
exaly   +3 more sources

Chest Imaging in Generalized Lymphatic Anomaly and Kaposiform Lymphangiomatosis

Pediatrics International, 2018
Hiroki Kato, Masayuki Matsuo, Michio Ozeki   +2 more
exaly   +3 more sources

Generalized Lymphatic Anomaly and Gorham–Stout Disease: Overview and Recent Insights [PDF]

Advances in Wound Care, 2019
Significance: Generalized lymphatic anomaly and Gorham–Stout disease are extremely rare diseases with severe symptoms and poor prognosis. The etiology and clinical presentation of the patients remain poorly defined, but recent research has attempted to determine the pathogenesis of these diseases.
Michio Ozeki, Toshiyuki Fukao
exaly   +3 more sources

Generalized lymphatic anomaly in adult patients: An eminently radiological diagnosis

Radiología (English Edition), 2023
Generalized lymphatic anomaly (GLA) is an uncommon congenital disease secondary to the proliferation of lymphatic vessels in any organ except the central nervous system. GLA has a wide spectrum of clinical and radiological presentations, among which osteolytic lesions are the most widespread, being the ribs the most commonly affected bone.
J, Sainz Sánchez, A, Aranaz Murillo, E, Andrés Villares, J, García Maroto   +3 more
openaire   +2 more sources

Radiographic, CT, and MRI Features of Generalized Lymphatic Anomaly in a Boy

Current Medical Imaging Reviews, 2023
Background: Generalized lymphatic anomaly (GLA) is a rare condition, mainly involving bones, soft tissue, and internal organs. The diagnosis of GLA is often difficult. Case presentation: We report a case of GLA in a boy who was initially treated for suspected Langerhans cell histiocytosis and discuss the potential imaging features of GLA.
Changwei, Ding, Yue, Wang
openaire   +2 more sources

Pathogenic variants inPIK3CAare associated with clinical phenotypes of kaposiform lymphangiomatosis, generalized lymphatic anomaly, and central conducting lymphatic anomaly

Pediatric Blood & Cancer, 2023
AbstractComplex lymphatic anomalies are debilitating conditions characterized by aberrant development of the lymphatic vasculature (lymphangiogenesis). Diagnosis is typically made by history, examination, radiology, and histologic findings. However, there is significant overlap between conditions, making accurate diagnosis difficult.
Jeremy M. Grenier, Alexandra J. Borst, Sarah E. Sheppard, Kristen M. Snyder, Dong Li, Lea F. Surrey, Alyaa Al‐Ibraheemi, David R. Weber, James R. Treat, Christopher L. Smith, Pablo Laje, Yoav Dori, Denise M. Adams, Michael Acord, Abhay S. Srinivasan   +14 more
openaire   +2 more sources