Results 81 to 90 of about 3,699,066 (293)
Pelatihan E-Learning Bagi Guru Untuk Optimalisasi Pembelajaran Generasi Z
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat, 2020 E-learning, the fusion between education and information technology, is the learning approach that suitable for the Z generation. E-learning implementation requires knowledge about e-learning concepts and skills to operate one of the e-learning ...
Sri Suhandiah +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Postculture Influence on Generation “Z”
Проблеми на постмодерносттаThis article aims to identify the characteristic features of postculture influencing the understanding of culture of generation Z. Culture itself is not seen as a kindred culture and spirit, but as an action and sensibility that passes from generation ...
Milena Vinarova
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Z Physics Constraints on Vector Leptoquarks
, 1996 We analyze the constraints on vector leptoquarks coming from radiative corrections to $Z$ physics. We perform a global fitting to the LEP data including the oblique and non-universal contributions of the most general effective Lagrangian for vector ...
Eboli, O. J. P. +2 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Z -> b\bar{b} Versus Dynamical Electroweak Symmetry Breaking involving the Top Quark
, 1994 In models of dynamical electroweak symmetry breaking which sensitively involve the third generation, such as top quark condensation, the effects of the new dynamics can show up experimentally in Z->b\bar{b}.
B. Pendleton +22 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source