Results 121 to 130 of about 405,858 (264)

A New Zero Waste Design for a Manufacturing Approach for Direct-Drive Wind Turbine Electrical Generator Structural Components

Machines
An integrated structural optimization strategy was produced in this study for direct-drive electrical generator structures of offshore wind turbines, implementing a design for an additive manufacturing approach, and using generative design techniques ...
Daniel Gonzalez-Delgado, Pablo Jaen-Sola, Erkan Oterkus   +2 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

3D constructing: Exploring the potential of 3D concrete and clay printing with generative design for architectural innovation

Informes de la Construccion
The architectural and construction sectors are experiencing a transformative shift with the advent of 3D constructing. This research delves into the potential of 3D printing technologies when combined with generative design principles to reshape ...
Javier Alonso Madrid, Guillermo Sotorrio, Nils Olsson, José Antonio Tenorio   +3 more
doaj   +1 more source

Structural Optimization Design of Dual Robot Gripper Unloading Device Based on Intelligent Optimization Algorithms and Generative Design. [PDF]

Sensors (Basel), 2023
Jia J, Sun X, Liu T, Tang J, Wang J, Hu X.   +5 more
europepmc   +1 more source

GENERAL DESIGNER

Internal Combustion Engines, 2014
Посвящается генеральному конструктору по двигателям средней мощности И.А. Ковалю. Приведены основные этапы и направления конструкторской и научной деятельности, достигнутые результаты в создании и обеспечении технического уровня дизелей для ...
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Generative Design and Additive Manufacturing Techniques on the Optimization of Multi-MW Offshore Direct-Drive Wind Turbine Electrical Generators

Engineering Proceedings
New advances in structural optimization techniques and manufacturing methods, such as generative design (GD) and additive manufacturing (AM), are revolutionizing the capabilities to generate high-efficiency and lightweight models in comparison with ...
Daniel Gonzalez-Delgado, Pablo Jaen-Sola, Erkan Oterkus   +2 more
doaj   +1 more source

Generative design for COVID-19 and future pathogens using stochastic multi-agent simulation. [PDF]

Sustain Cities Soc, 2023
Lee B, Lau D, Mogk JPM, Lee M, Bibliowicz J, Goldstein R, Tessier A.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Towards a Generative Frame System of Ancient Chinese Timber Architecture: Structural Generation and Optimization of “Column Reduction” and “Column Relocation”

Buildings
In traditional Chinese timber architecture, “column reduction” (Jian Zhu Zao) and “column relocation” (Yi Zhu Zao) enhances spatial continuity, yet often produces bending-dominated, material-intensive frames. This study develops a generative frame system
Tonghao Liu, Binyue Zhang, Yamin Zhao
doaj   +1 more source