Results 121 to 130 of about 394,851 (262)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analysis of the application of generative artificial intelligence in interior design education

Ain Shams Engineering Journal
The rapid advancement of artificial intelligence (AI) has introduced generative AI tools as transformative resources in interior design education, enhancing creativity, aesthetic quality, and practical design outcomes.
Yao Liu, Beiyuan Xu, Jiarong Feng, Pengjun Wu   +3 more
doaj   +1 more source

Generative design for COVID-19 and future pathogens using stochastic multi-agent simulation. [PDF]

Sustain Cities Soc, 2023
Lee B, Lau D, Mogk JPM, Lee M, Bibliowicz J, Goldstein R, Tessier A.   +6 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Use of Generative AI to Support Inclusivity and Design Deliberation for Online Instruction

Online Learning
Generative AI presents significant opportunities for instructional designers to revolutionize content creation and personalization in online learning environments.
Jill Stefaniak, Stephanie Moore
doaj   +1 more source

Generative design of large-scale fluid flow structures via steady-state diffusion-based dehomogenization. [PDF]

Sci Rep, 2023
Hankins SN, Zhou Y, Lohan DJ, Dede EM.
europepmc   +1 more source

GENERAL DESIGNER

Internal Combustion Engines, 2014
Посвящается генеральному конструктору по двигателям средней мощности И.А. Ковалю. Приведены основные этапы и направления конструкторской и научной деятельности, достигнутые результаты в создании и обеспечении технического уровня дизелей для ...
openaire   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A New Zero Waste Design for a Manufacturing Approach for Direct-Drive Wind Turbine Electrical Generator Structural Components

Machines
An integrated structural optimization strategy was produced in this study for direct-drive electrical generator structures of offshore wind turbines, implementing a design for an additive manufacturing approach, and using generative design techniques ...
Daniel Gonzalez-Delgado, Pablo Jaen-Sola, Erkan Oterkus   +2 more
doaj   +1 more source

Optimizing efficiency in the creation of patient-specific plates through field-driven generative design in maxillofacial surgery. [PDF]

Sci Rep, 2023
Tel A, Kornfellner E, Moscato F, Vinayahalingam S, Xi T, Arboit L, Robiony M.   +6 more
europepmc   +1 more source