Results 51 to 60 of about 2,343,217 (327)

The Aging Features of Thyrotoxicosis Mice: Malnutrition, Immunosenescence and Lipotoxicity

open access: yesFrontiers in Immunology, 2022
The problem of aging is mainly the increase of age-related diseases, and elderly patients have longer hospitalization and worse prognosis. Poorer nutritional status and immunosenescence may be predisposing and severe factors.
Qin Feng   +6 more
doaj   +1 more source

Generic uniqueness of a structured matrix factorization and applications in blind source separation

open access: yes, 2016
Algebraic geometry, although little explored in signal processing, provides tools that are very convenient for investigating generic properties in a wide range of applications. Generic properties are properties that hold "almost everywhere". We present a
DeLathauwer, Lieven, Domanov, Ignat
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Key Factors for Improving Predictive Accuracy and Avoiding Overparameterization of the PBPK Absorption Model in Food Effect Studies of Weakly Basic Water-Insoluble Compounds in Immediate Release Formulations

open access: yesPharmaceutics
Background/Objectives: Physiologically based pharmacokinetic (PBPK) absorption models are instrumental for assessing drug absorption prior to clinical food effect studies, though discrepancies in predictive and actual outcomes are observed.
Miao Zhang   +5 more
doaj   +1 more source

Kummer covers and braid monodromy

open access: yes, 2015
In this work we describe a method to reconstruct the braid monodromy of the preimage of a curve by a Kummer cover. This method is interesting, since it combines two techniques, namely, the reconstruction of a highly non-generic braid monodromy with a ...
Artal   +17 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Ergodic theory of generic continuous maps

open access: yes, 2012
We study the ergodic properties of generic continuous dynamical systems on compact manifolds. As a main result we prove that generic homeomorphisms have convergent Birkhoff averages under continuous observables at Lebesgue almost every point. In spite of
Abdenur, Flávio, Andersson, Martin
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Distinguishability of generic quantum states

open access: yes, 2016
Properties of random mixed states of order $N$ distributed uniformly with respect to the Hilbert-Schmidt measure are investigated. We show that for large $N$, due to the concentration of measure, the trace distance between two random states tends to a ...
Pawela, Łukasz   +2 more
core   +1 more source

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