Results 81 to 90 of about 351,529 (205)

The Distortionary Effects of Government Procurement: Evidence from Medicaid Prescription Drug Purchasing [PDF]

The federal-state Medicaid program insures 43 million people for virtually all of the prescription drugs approved by the FDA. To determine the price that it will pay for a drug treatment, the government uses the average price in the private sector for ...
Fiona Scott Morton, Mark Duggan
core  

_M. tuberculosis_ interactome analysis unravels potential pathways to drug resistance [PDF]

, 2008
Drug resistance is a major problem for combating tuberculosis. Lack of understanding of how resistance emerges in bacteria upon drug treatment limits our ability to counter resistance.
Karthik Raman, Nagasuma Chandra
core   +1 more source

Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

CPT: Pharmacometrics & Systems Pharmacology
By applying nonlinear mixed‐effect (NLME) models, model‐integrated evidence (MIE) approaches are able to analyze bioequivalence (BE) data with pharmacokinetic end points that have sparse sampling, which is problematic for non‐compartmental analysis (NCA).
Xiaomei Chen, Henrik B. Nyberg, Mark Donnelly, Liang Zhao, Lanyan Fang, Mats O. Karlsson, Andrew C. Hooker   +6 more
doaj   +1 more source

Value-Based Generic Drug Evaluation Focus on Chinese Real-World Evidence. [PDF]

Int J Health Policy Manag, 2023
Lu J, Ying X, Li Z.
europepmc   +1 more source

Estimations of generic drug entry in Brazil using count versus ordered models [PDF]

, 2010
Two major changes in Brazilian legislation during the 1990s reshaped the local pharmaceutical industry: the ratification of the TRIPS agreement including a provision for pipeline inventions in 1996, and a Generic Drug Act in 1999, which introduced ...
Caballero, Barbara, Fiuza, Eduardo P. S.
core  

Generic Drugs [PDF]

Diabetes Care, 2007
openaire   +2 more sources

Increasing impact of quantitative methods and modeling in establishment of bioequivalence and characterization of drug delivery

CPT: Pharmacometrics & Systems Pharmacology, 2023
Miyoung Yoon, Andrew Babiskin, Meng Hu, Fang Wu, Sam G. Raney, Lanyan Fang, Liang Zhao   +6 more
doaj   +1 more source

Neurotoxicological Evaluation of Intrathecal Citrate Excipients: Calcium Homeostasis Disruption and Safety Implications in CNS Drug Delivery

Pharmaceutics
Background/Objectives: Intrathecal drug delivery is essential for treating CNS disorders, but the safety of commonly used excipients such as citric acid/sodium citrate (SC) remains unclear.
Jue Wang, Yuan Zhang, Qing He, Ying Du, Xia Zhang, Xinru Tan, Xinting Zhou, Susu Tang, Baoming Ning, Rui Yang, Xia Zhao, Dejiang Tan, Huimin Sun, Jiasheng Tu   +13 more
doaj   +1 more source

An empirical study of the impact of generic drug competition on drug market prices in China. [PDF]

Front Public Health, 2023
Yina C, Pengcheng L, Haomiao N, Yang C.
europepmc   +1 more source

FDA Approval of Drugs and Devices: Preemption of State Laws for “Parallel” Tort Claims [PDF]

, 2015
The U.S. Supreme Court’s important ruling in Mutual Pharmaceutical Co., Inc. v. Bartlett concerns whether the Food and Drug Administration’s (“FDA”) approval of a generic drug insulates the drug manufacturer from liability under state tort laws from ...
Boumil, Marcia
core