Results 141 to 150 of about 71,732 (246)

Multi-Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring. [PDF]

J Cachexia Sarcopenia Muscle
Liu R, She J, Li X, Yan Y, Mo J, Sheng J, Yang H, Huang H.   +7 more
europepmc   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Prevalence, Antimicrobial Susceptibility, and Molecular Characteristics of Ceftazidime-Avibactam-Resistant <i>Klebsiella pneumoniae</i> in a Chinese Hospital. [PDF]

Infect Drug Resist
Li J, Wang H, Liu Z, Xia Y, Hu Y, Wang H, Xia F, Zou M.   +7 more
europepmc   +1 more source

Egg yolk hydrolysate shows moderate impact on osteoporosis in ovariectomized rats

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study investigated the protective effect of egg yolk hydrolysate (FC) on osteoporosis in ovariectomized (OVX) rats, a well‐established model of postmenopausal bone loss. OVX rats were fed diets supplemented with 0.2% or 1% FC for 13 weeks.
Ilekuttige Priyan Shanura Fernando, Da Shi, Zihan Wang, Michael Doschak, Jianping Wu   +4 more
wiley   +1 more source

FOS and JUN regulate oxidative stress and steroidogenesis in human aldosterone-producing adenomas. [PDF]

Redox Biol
Wei J, Duregon E, Papotti MG, Knösel T, Bidlingmaier M, Sbiera S, Reincke M, Williams TA.   +7 more
europepmc   +1 more source

Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro. ADSCs were exposed to various puerarin concentrations to assess cell proliferation, osteogenic differentiation, and ...
Ting Yang, Xu Zhang, Liang‐Fu Zhang
wiley   +1 more source

Fmoc-DDT@Fos hydrogel mitigates temporomandibular joint osteoarthritis through regulating macrophage reprogramming and ferroptosis. [PDF]

Mater Today Bio
Zhang Y, Zhang D, Yue X, Xu Q, Bu L, Lu J, Yang C, Shen P, Zheng J.   +8 more
europepmc   +1 more source

Soil Nail Design Optimization Through Adaptive Slope Stability Analysis Using Improved Limit Equilibrium Method

International Journal for Numerical and Analytical Methods in Geomechanics, EarlyView.
ABSTRACT Design optimization for automatically generating optimal design results is a promising technique for enhancing the efficiency of design processes and outcomes. However, its development for soil nail reinforced slopes is limited since the traditional slope stability analysis using the limit equilibrium method (LEM) becomes relatively time ...
Weihang Ouyang, Kai Liu, Si‐Wei Liu
wiley   +1 more source

Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation. [PDF]

Front Immunol
Du L, Pan J, Xu N, Yan F, Tian W, Li Q.
europepmc   +1 more source

Engaging the public in plant science: Communication facilitators and barriers of scaling up a citizen science campaign

People and Nature, EarlyView.
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson, Monika Suškevičs, Baiba Prūse, Marta Barberis, Sara A. O. Cousins, Živa Fišer, Margaux Julien, Marianne Kivastik, Marcin Klisz, Attila Lengyel, Zuzana Münzbergová, Radosław Puchałka, Iris Reinula, Froukje Rienks, Julie Koch Sheard, Viktor Siverin, Bojana Stojanova, Sabrina Träger, Tsipe Aavik   +18 more
wiley   +1 more source