Results 141 to 150 of about 5,543,352 (313)

Therapeutic targets for diabetic nephropathy identified by druggable genome mendelian randomization: the role of the gut microbiota-metabolite axis. [PDF]

Front Endocrinol (Lausanne)
Niu L, Ma R, Miao C, Liu F, Li B.
europepmc   +1 more source

A FOS/NFKB1-associated Hofbauer cell subset mediates placental niche dysregulation in early-onset fetal growth restriction. [PDF]

Front Cell Dev Biol
Sun Y, Lin H, Zhu W, Niu L, Li Y, Huang Y, Chang Q.   +6 more
europepmc   +1 more source

TET3 promotes preeclampsia by regulating PDK4-mediated glucose metabolism reprogramming in trophoblasts. [PDF]

iScience
Deng X, Liu Y, Li M, Tang W, Jiang L, Rahman J, Sagnelli M, Hu H, Sun L, Zuo Q, Wu D, Xu Y.   +11 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Cranberry juice potentiates sensitivity of uropathogenic <i>Escherichia coli</i> (UPEC) strains to fosfomycin and decreases occurrence of spontaneous resistance. [PDF]

Appl Environ Microbiol
Groleau M-C, Houle S, Quevedo AC, McKay G, Nguyen D, Dozois CM, Tufenkji N, Déziel E.   +7 more
europepmc   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Identification of tumor-promoting functions of the Homeobox family transcription factor MSX1 in cervical cancer. [PDF]

Cell Death Discov
Brücker P, Horn S, Jansari S, Kombou M, Eppich S, Jeschke U, Hakroush S, Küffer S, Fritzsche S, Wegwitz F, Gallwas J.   +10 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

Identification and analysis of diagnostic senescence-related gene signatures for acute myocardial infarction based on multi-omics data and machine learning. [PDF]

Front Immunol
Zhang H, Huang H, Jiang Z, Qian S, Jin X, Peng Z, Huang F, Li P, Wei L, Qi Z, Qi X.   +10 more
europepmc   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source