Exploring the molecular mechanism of Qingzao Decoction in the treatment of IgA vasculitis through network pharmacology and molecular docking. [PDF]
Shi Y, Ao Y, Zheng D, Liu C, Li H.
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Lactate attenuates hepatic ischemia-reperfusion injury by reducing intrahepatic inflammation and suppressing hepatocyte-neutrophil interaction via the IL-33/ST2 pathway. [PDF]
Fang P +11 more
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Activator protein-1 (AP-1) inhibition prevents endothelial to mesenchymal transition in diabetes-associated atherosclerosis: a translational study. [PDF]
Khan AW +11 more
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The two faces of MyoD: repressor and activator of gene expression during myogenesis. [PDF]
Birchmeier C.
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Sleep and wakefulness in c-fos and fos B gene knockout mice
Molecular Brain Research, 2000G-protein coupled receptor (GPCR) stimulation has been implicated in the regulation of sleep. Upon stimulation of a GPCR an intracellular cascade involving second and third messengers is initiated. The latter include the fos-family of immediate early genes (IEGs). Although there is considerable evidence indicating that IEGs are expressed in response to
P J, Shiromani +5 more
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c-fos antisense RNA blocks expression of c-fos gene in F9 embryonal carcinoma cells
Cell Differentiation and Development, 1988To study the function of proto-oncogene c-fos, we prepared an antisense plasmid that expresses in mammalian cells c-fos antisense RNA which is complementary to the endogenous c-fos mRNA. Upon transfection into undifferentiated F9 EC cells, the antisense plasmid directed constitutive expression of a large amount of c-fos antisense RNA.
B Z, Levi, J W, Kasik, K, Ozato
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Alteration of c-fos gene methylation in human gliomas
Molecular Carcinogenesis, 1996In an attempt to find a common DNA alteration occurring in human glioma, we examined DNA methylation in 34 gliomas of various pathological grades and compared them with those in normal cerebral subcortex DNA. The total methylated cytosine levels in the genome did not differ appreciably between the tumors and the normal tissues; however, the degree of ...
S, Uyeno +11 more
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A remarkable discovery of the past few years is the fact that many acutely oncogenic retroviruses contain sequences as an integral part of their genome which have homologs in normal cells (1). Acquisition of normal cellular sequences by retroviruses, usually at the expense of genes required for replication, enables them to induce neoplasias in vivo and
I. M. Verma +3 more
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Induction of c-fosGene Expression by Interferons
Journal of Interferon Research, 1988We show that murine interferons (IFNs)-alpha/beta and -gamma induce expression of the protooncogene c-fos in F9 embryonal carcinoma cells, NIH-3T3 cells, and other tissue culture cells. The induction of c-fos mRNA is rapid and transient in that the mRNA appears within 15 min and disappears by 2 h following IFN treatment. The protein synthesis inhibitor
Y J, Wan, B Z, Levi, K, Ozato
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Complementary DNA clones of genes induced by platelet-derived growth factor (PDGF) in BALB/c-3T3 cells were isolated; one such clone contains a domain having nucleotide sequence homology with the third exon of c- fos .
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