Results 251 to 260 of about 5,543,352 (313)

Molecular mechanisms for somatostatin inhibition of c-fos gene expression

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1997
We reported previously that somatostatin inhibits the expression of the immediate early gene c-fos. Accordingly, we characterized the molecular mechanisms by which somatostatin inhibits c-fos gene expression. Because growth factors activate c-fos through a region of its promoter known as the serum response element [SRE; base pairs (bp) -357 to -276 ...
A, Todisco, Y, Takeuchi, J, Yamada, J I, Sadoshima, T, Yamada   +4 more
openaire   +2 more sources

The c-fos gene and early-onset familial Alzheimer's disease

Neuroscience Letters, 1993
A gene for early-onset familial Alzheimer's disease (FAD) is located on chromosome 14q24.3. The c-fos gene (FOS) is also located in the same band of this chromosome and is thus a candidate for the FAD locus. A yeast artificial chromosome (YAC) clone was identified which contains FOS.
Lori L.C. Bonnycastle, Chang-En Yu, Ellen M. Wijsman, Harry T. Orr, David Patterson, Kevin P. Clancy, Katrina A.B. Goddard, M.Elisa Alonso, Ellen Nemens, June A. White, Leonard L. Heston, George M. Martin, Thomas D. Bird, Gerard D. Schellenberg   +13 more
openaire   +2 more sources

Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini

Cell, 1983
The complete nucleotide sequence of the FBJ-MuSV proviral DNA and the cellular homolog (c-fos) of its oncogene (v-fos) have been determined. The 4026 nucleotide long FBJ-MuSV proviral DNA contains two long terminal repeats, a substitution of 1639 nucleotides of mouse cellular DNA (v-fos) and the 3' end of the env gene derived from FBJ-MuLV.
C, Van Beveren, F, van Straaten, T, Curran, R, Müller, I M, Verma   +4 more
openaire   +2 more sources

The gene structure of the Drosophila melanogaster proto-oncogene, kayak, and its nested gene, fos-intronic gene

Gene, 2008
We present herein a new model for the structure of the Drosophila kayak gene as well as preliminary data on the functional differences of its various isoforms. kayak is a homolog of the human proto-oncogene, c-fos. kayak has three different starts of transcription, and therefore promoters (P)kay-alpha, (P)kay-beta and (P)kay-gamma.
Stephanie Gidget, Hudson, Elliott S, Goldstein   +1 more
openaire   +2 more sources

Proto-oncogene fos: an inducible multifaceted gene.

Symposium on Fundamental Cancer Research, 1988
Proto-oncogene fos, which is expressed during cell growth and cell differentiation and development, is a multifaceted gene. The viral homolog, v-fos, was identified as the resident transforming gene of FBJ-murine osteosarcoma virus, which induces bone tumors in mice. Owing to an in-frame deletion during the biogenesis of the v-fos gene, the products of
R L, Mitchell, S K, Hanks, I M, Verma
openaire   +1 more source

c-Fos antagonizes the junD gene positive autoregulatory loop; a novel c-Fos role in promoter switching

Gene, 1998
In contrast to c-jun and junB, the junD gene is constitutively expressed in quiescent cells. The junD promoter, therefore, may provide a paradigm for promoters mostly active in growth arrested cells. We report here that the human junD promoter is repressed by serum and TPA.
I, Berger, Y, Shaul
openaire   +2 more sources

A Fos-Jun element in the first intron of an α2u-globulin gene

Molecular and Cellular Biochemistry, 1993
The hepatic expression of the alpha-2u-globulin gene family is controlled by a variety of hormones including steroids, growth hormone and insulin. The mechanisms by which these hormones affect alpha 2u-globulin expression are only partially understood. Recently we isolated and characterized clone RAP 01, an alpha 2u-globulin gene expressed in the liver.
P, van Dijck, K, Schoonjans, P, Sassone-Corsi, J, Auwerx, G, Verhoeven   +4 more
openaire   +2 more sources

Fos-transformation activates genes associated with invasion.

Oncogene, 1994
Fos oncoproteins transform cells by functioning as transcription factors. Over-expression of c-fos results in minimal morphological transformation while the two viral isolates, FBJ and FBR v-fos, result in full morphological transformation. Fos-transformed cells are serum dependent for proliferation but not for morphological transformation. To identify
R F, Hennigan, K L, Hawker, B W, Ozanne
openaire   +1 more source

The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3

FEBS Letters, 2011
D. Schiavone, L. Avalle, S. Dewilde, V. Poli   +3 more
semanticscholar   +1 more source

Differential expression of mitogen-activated protein kinases and immediate early genes fos and jun in thalamus in schizophrenia.

Progress in Neuro-psychopharmacology and Biological Psychiatry, 2004
S. Kyosseva
semanticscholar   +1 more source