Results 41 to 50 of about 25,117 (218)
Island biogeography can promote rapid diversification and speciation via geographic isolation and novel selection pressures. These same factors can threaten the persistence of island endemics by limiting gene flow and suitable habitat.
McIntyre A. Barrera +2 more
doaj +1 more source
The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease [PDF]
The dramatic recent rise in the incidence of allergic or autoimmune inflammatory diseases in the West has been proposed to reflect the lack of appropriate priming of the immune response by infectious agents such as parasitic worms during childhood ...
Al-Riyami +111 more
core +2 more sources
Searching for antigen B genes and their adaptive sites in distinct strains and species of the helminth Echinococcus [PDF]
Twenty-seven PCR-derived antigen B (AgB) nucleotide sequences from four Echinococcus species (Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthrus and Echinococcus vogeli) were aligned with 78 already published sequences, to generate a maximum likelihood phylogeny of the AgB multigene family. The phylogenetic analysis confirms
Haag, KL +5 more
openaire +4 more sources
Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Adler +133 more
core +1 more source
Background Infectious bovine keratoconjunctivitis (IBK) or ‘pinkeye’ is an economically important ocular disease that significantly impacts animal performance.
Ali Abdirahman A +3 more
doaj +1 more source
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (ECM),
Pia M. Vornewald +9 more
doaj +1 more source
Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine.
A A, Badawy +4 more
openaire +2 more sources
Natural variation in immune responses to neonatal mycobacterium bovis bacillus calmette-guerin (BCG) vaccination in a cohort of Gambian infants [PDF]
Background There is a need for new vaccines for tuberculosis (TB) that protect against adult pulmonary disease in regions where BCG is not effective.
A Lalvani +46 more
core +3 more sources
Genomic analyses of aminoacyl tRNA synthetases from human-infecting helminths
Background Helminth infections affect ~ 60% of the human population that lives in tropical and subtropical regions worldwide. These infections result in diseases like schistosomiasis, lymphatic filariasis, river blindness and echinococcosis.
Preeti Goel, Suhel Parvez, Amit Sharma
doaj +1 more source
Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen [PDF]
Since interleukin (IL)-10 is a key mediator of immunosuppression, and immunosuppression is considered an important element of helminth infection, we studied variants of the putative IL-10 gene promoter in 337 individuals from 130 families heavily exposed to infection by the tissue nematode Onchocerca volvulus.
C, Timmann +8 more
openaire +2 more sources

