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Island biogeography can promote rapid diversification and speciation via geographic isolation and novel selection pressures. These same factors can threaten the persistence of island endemics by limiting gene flow and suitable habitat.
McIntyre A. Barrera +2 more
doaj +1 more source
Local cytokine transcription in naïve and previously infected sheep and lambs following challenge with Teladorsagia circumcincta [PDF]
<b>Background</b><p></p> The abomasal helminth Teladorsagia circumcincta is one of the most economically important parasites affecting sheep in temperate regions.
Craig, Nicola M +4 more
core +3 more sources
Searching for antigen B genes and their adaptive sites in distinct strains and species of the helminth Echinococcus [PDF]
Twenty-seven PCR-derived antigen B (AgB) nucleotide sequences from four Echinococcus species (Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthrus and Echinococcus vogeli) were aligned with 78 already published sequences, to generate a maximum likelihood phylogeny of the AgB multigene family. The phylogenetic analysis confirms
Haag, KL +5 more
openaire +4 more sources
Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine.
A A, Badawy +4 more
openaire +2 more sources
The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild
Parasitic helminths are extremely resilient in their ability to maintain chronic infection burdens despite (or maybe because of) their hosts’ immune response.
Simon A. Babayan +6 more
doaj +1 more source
Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
Maizels, R M
core +1 more source
Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen [PDF]
Since interleukin (IL)-10 is a key mediator of immunosuppression, and immunosuppression is considered an important element of helminth infection, we studied variants of the putative IL-10 gene promoter in 337 individuals from 130 families heavily exposed to infection by the tissue nematode Onchocerca volvulus.
C, Timmann +8 more
openaire +2 more sources
Background Infectious bovine keratoconjunctivitis (IBK) or ‘pinkeye’ is an economically important ocular disease that significantly impacts animal performance.
Ali Abdirahman A +3 more
doaj +1 more source
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (ECM),
Pia M. Vornewald +9 more
doaj +1 more source
The Echinococcus canadensis (G7) genome: A key knowledge of parasitic platyhelminth human diseases [PDF]
Background: The parasite Echinococcus canadensis (G7) (phylum Platyhelminthes, class Cestoda) is one of the causative agents of echinococcosis. Echinococcosis is a worldwide chronic zoonosis affecting humans as well as domestic and wild mammals, which ...
A Bankevich +109 more
core +8 more sources

