Results 101 to 110 of about 5,454,912 (236)

Homeobox genes: going for growth [PDF]

Gut, 2002
The role of homeobox genes and dietary factors in gut growth and differentiation In this issue of Gut , Domon-Dell and colleagues1 report the influence of butyrate on the intestinal homeobox gene Cdx2 [ see page 525 ]. Butyrate is a byproduct of fibre fermentation by colonic bacteria and is known to be a substrate for colonocytes.
openaire   +2 more sources

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia.

PLoS ONE, 2020
The NKL-code describes normal expression patterns of NKL homeobox genes in hematopoiesis. Aberrant expression of NKL homeobox gene subclass members have been reported in several hematopoietic malignancies including acute myeloid leukemia (AML).
Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler   +4 more
doaj   +1 more source

Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer

Breast Cancer Research, 2009
IntroductionAberrant methylation of CpG islands is a hallmark of cancer and occurs at an early stage in breast tumorigenesis. However, its impact on tumor development is not fully determined, and its potential as a diagnostic biomarker remains to be ...
S. Tommasi, Deborah L Karm, Xiwei Wu, Y. Yen, G. Pfeifer   +4 more
semanticscholar   +1 more source

Transcriptomic comparison analysis across seven developmental stages of the Triatoma rubrofasciata, a vector of Chagas disease

BMC Genomics
Background Triatoma rubrofasciata is an obligate hematophagous insect and a primary vector of Trypanosoma cruzi, the etiological agent of Chagas disease, with a widespread global distribution. In addition to Try. cruzi, T.
Lei Duan, Yunjia Tian, Ziyi Wang, Limin Yang, Yunhai Guo, Yuanyuan Li, Zhengbin Zhou, Yong Shen, Yi Zhang, Qin Liu   +9 more
doaj   +1 more source

A symphony of inner ear developmental control genes

BMC Genetics, 2010
The inner ear is one of the most complex and detailed organs in the vertebrate body and provides us with the priceless ability to hear and perceive linear and angular acceleration (hence maintain balance).
Kraus Petra, Chatterjee Sumantra, Lufkin Thomas   +2 more
doaj   +1 more source

A dynamic regulome of shoot-apical-meristem-related homeobox transcription factors modulates plant architecture in maize

Genome Biology
Background The shoot apical meristem (SAM), from which all above-ground tissues of plants are derived, is critical to plant morphology and development. In maize (Zea mays), loss-of-function mutant studies have identified several SAM-related genes, most ...
Zi Luo, Leiming Wu, Xinxin Miao, Shuang Zhang, Ningning Wei, Shiya Zhao, Xiaoyang Shang, Hongyan Hu, Jiquan Xue, Tifu Zhang, Fang Yang, Shutu Xu, Lin Li   +12 more
doaj   +1 more source

IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia.

PLoS ONE
Homeobox genes encode transcription factors which organize differentiation processes in all tissue types including the hematopoietic compartment. Recently, we have reported physiological expression of TALE-class homeobox gene IRX1 in early myelopoiesis ...
Stefan Nagel, Corinna Meyer, Claudia Pommerenke   +2 more
doaj   +1 more source

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi, David Dawson, Donald Rao, Francesco DeMayo, John Nemunaitis, Kelly Stehling, Marie-Claude Gingras, Michael Norman, Nancy Templeton, Neil Senzer, Richard Gibbs, Shi-He Liu, William Fisher, Zhaohui Wang   +13 more
core   +1 more source

Homeobox genes in gut development

Gut, 2002
Classical descriptions of gut development specify subdivision into foregut, midgut, and hindgut together with their derivatives. This is based on the anatomical localisation of the anterior and posterior intestinal portals separating the roof of the yolk sac from the foregut and hindgut diverticulae.
openaire   +4 more sources

The last common bilaterian ancestor [PDF]

, 2002
Many regulatory genes appear to be utilized in at least superficially similar ways in the development of particular body parts in Drosophila and in chordates.
Davidson, Eric H., Erwin, Douglas H.
core