Results 161 to 170 of about 73,647 (262)

Early‐Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection

MedComm, Volume 7, Issue 8, August 2026.
EOPC is a distinct clinicopathological entity separable from SOPC, differing fundamentally in genetic susceptibility, TMPRSS2:ERG fusion frequency, and survival outcomes. Although research remains nascent, this review provides the first comprehensive synthesis of current evidence, offering a critical foundation to guide future investigations into this ...
Xingyu Xiong, Weizhen Zhu, Weichao Huang, Shiyu Zhang, Qi Deng, Jie Yang, Hang Xu, Qiang Wei, Lu Yang   +8 more
wiley   +1 more source

Nasal Retinal Degeneration Is a Feature of a Subset of <i>CRX</i>-Associated Retinopathies. [PDF]

Genes (Basel)
Massengill MT, Juvier Riesgo T, Davis JL, Mendoza-Santiesteban CE, Goldhagen BE, Lam BL, Gregori NZ.   +6 more
europepmc   +1 more source

Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7149-7160, August 2026.
ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann, Cedric Wilden, Leticia Prates‐Roma, Matthias W. Laschke, Emmanuel Ampofo, Selina Wrublewsky   +5 more
wiley   +1 more source

Genetics of Flooding Tolerance in an F2 Miscanthus sacchariflorus ssp. lutarioriparius × M. sinensis Population

GCB Bioenergy, Volume 18, Issue 8, August 2026.
An experiment to map flooding tolerance in Miscanthus ×giganteus was conducted. Two phenotyping protocols (A and B) and different pipelines to call SNPs were used. TASSEL‐GBSv2 resulted in a genetic map with smaller QTL intervals than the other maps.
D. Zerpa‐Catanho, L. Xiao, N. LaBonte, Y. Yoshinaga, M. Blow, K. Barry, X. Kuang, E. Cebert, T. Mitros, D. Rokhsar, K. Swaminathan, E. J. Sacks   +11 more
wiley   +1 more source

Identification and characterization of the <i>KNOTTED1-like</i> homeobox as an active regulator of leaf development in chickpea. [PDF]

Front Plant Sci
Gutierrez N, Castro P, Rubio J, Die JV.
europepmc   +1 more source

EMF2 deficiency disrupts epigenetic and chromatin organization landscapes, blocking root regeneration competence in Arabidopsis

New Phytologist, Volume 251, Issue 4, Page 1792-1810, August 2026.
EMF2 mutation alters transcriptomic profiles in Arabidopsis calli while retaining responsiveness during root induction. Summary Plant de novo organogenesis depends on callus formation, yet the epigenetic mechanisms governing organ regeneration remain poorly understood.
Zhidan Wang, May Avraham, Tali Mandel, Leor Eshed Williams, Chang Liu   +4 more
wiley   +1 more source

Differential activity of transcription factors and neuronal effectors during the development of pikeperch brain. [PDF]

Biol Open
Symonová R, Jůza T, Tesfaye M, Brabec M, Sajdlová Z, Brabec J, Kubečka J.   +6 more
europepmc   +1 more source

The GSK3/SHAGGY‐like OsGSK3 phosphorylates and inhibits phase separation of OsFCA at Ser‐43 and Ser‐45 to regulate brassinosteroid signaling and rice architecture

New Phytologist, Volume 251, Issue 4, Page 1909-1929, August 2026.
A working model for GLYCOGEN SYNTHASE KINASE 3‐mediated phosphorylation of FLOWERING CONTROL LOCUS A in the regulation of brassinosteroid signaling and rice growth and development. Summary Brassinosteroid (BR) signaling plays a critical role in rice (Oryza sativa L.) grain development.
Jiaqi Zhang, Fan Wang, Sijia Zhang, Qian Yu, Qimiao Dong, Jianbo Li, Xianglei Wei, Huaying Du, Ye Shen, Rong Mu, Yanxiao Jia, Jinping Cheng, Hongsheng Zhang, Ji Huang, Xiuying Gao   +14 more
wiley   +1 more source

Single-cell and spatial transcriptomics reveal that the CXCL12-CXCR4 axis drives the immune-desert phenotype in small cell lung cancer by recruiting immunosuppressive CXCR4⁺ neutrophils and S100A8⁺ monocytes. [PDF]

J Immunother Cancer
Zeng P, Li HF, Shu WB, Zhang J, Zhao TC, Hu JW, Wang JF, Wang C, Lu QY, Yang JH, An YL, Chen R.   +11 more
europepmc   +1 more source

Root hair plasticity in cereals under abiotic stress

New Phytologist, Volume 251, Issue 4, Page 1684-1693, August 2026.
An integrative perspective on how to study the regulation of root hair plasticity to increase the resilience of cereals to abiotic stress. Summary Abiotic stress is a constant threat to crop growth and yield in the context of climate change. Root systems that can best adapt their architecture to environmental challenges contribute to enhanced ...
Yaping Zhou, Frank Hochholdinger
wiley   +1 more source