Results 31 to 40 of about 239,792 (215)

MYC-type transcription factors, MYC67 and MYC70, interact with ICE1 and negatively regulate cold tolerance in Arabidopsis

Scientific Reports, 2018
The expression of hundreds of genes is induced by low temperatures via a cold signaling pathway. ICE1, a MYC-type transcription factor, plays an important role in the induction of CBF3/DREB1A to control cold-responsive genes and cold tolerance.
Masaru Ohta, Aiko Sato, Na Renhu, Tsuyoshi Yamamoto, Nodoka Oka, Jian-Kang Zhu, Yasuomi Tada, Takuya Suzaki, Kenji Miura   +8 more
doaj   +1 more source

MYC and N-MYC are overexpressed in MYC-ER and N-MYC-ER-expressing cells, and naturally overexpressed MYC controls circadian gene expression.

, 2023
A.MYCN was determined in parental SKNAS, SKNAS N-MYC-ER, or SHEP N-MYC-ER by qPCR in n = 3 replicates by quantitative PCR (qPCR), normalized to β2M. MYCN overexpression is shown relative to parental SKNAS, since SHEP do not express MYCN. B.
Brian J. Altman (16819407), Aalim M. Weljie (244968), Chi V. Dang (9424989), Stephano S. Mello (15101894), Rebekah Brooks (16819404), Siti Noor Ain Binti Ahmad Shahidan (16819392), Zandra E. Walton (16819401), Jamison B. Burchett (9707399), Daniel Mwangi (16819395), Rachel E. DeRollo (16819389), Annie L. Hsieh (16819398), Saikumari Krishnaiah (4433761), Juliana Cazarin (16819386)   +12 more
core   +1 more source

The N-myc gene product in primary retinoblastomas [PDF]

Cancer, 1989
The N-myc gene product in retinoblastomas was examined using the antisera against the N-myc gene product, which was produced as a fusion protein by Escherichia coli. The N-myc gene product was detected not only in the retinoblastoma cell line Y79 but also in primary retinoblastomas as a pair of bands of approximately 62 kilodaltons (KD) by ...
T, Yokoyama, T, Tsukahara, C, Nakagawa, T, Kikuchi, K, Minoda, H, Shimatake   +5 more
openaire   +2 more sources

Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma

Acta Neuropathologica Communications, 2020
Medulloblastoma, a highly malignant pediatric brain tumor, consists of four molecular subgroups, namely WNT, SHH, Group 3, and Group 4. The expression of miR-193a, a WNT subgroup-specific microRNA, was found to be induced by MYC, an oncogenic target of ...
Harish Shrikrishna Bharambe, Annada Joshi, Kedar Yogi, Sadaf Kazi, Neelam Vishwanath Shirsat   +4 more
doaj   +1 more source

Nuclear AXIN2 represses MYC gene expression [PDF]

Biochemical and Biophysical Research Communications, 2014
The β-catenin transcriptional coactivator is the key mediator of the canonical Wnt signaling pathway. In the absence of Wnt, β-catenin associates with a cytosolic and multi-protein destruction complex where it is phosphorylated and targeted for proteasomal degradation.
Sherri A, Rennoll, Wesley M, Konsavage, Gregory S, Yochum   +2 more
openaire   +2 more sources

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts [PDF]

, 2013
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response.
Shi, Xiao-Hua, Shi, XH, Jacob C. Larkin, Baosheng Chen, Xiao-Hua Shi (2286394), Larkin Jacob C., Larkin, Jacob C., Yoel Sadovsky, Baosheng Chen (294603), Larkin, JC, Chuang, Eric Y., Jacob C Larkin, Chen Baosheng, Sadovsky, Y, Shi Xiao-Hua, Chen, Baosheng, Sadovsky, Yoel, Sadovsky Yoel, Yoel Sadovsky (199874), Jacob C. Larkin (459267), Chen, B, Xiao-Hua Shi, Larkin, Jacob C   +22 more
core   +1 more source

Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR). [PDF]

PLoS ONE, 2010
We investigated mTOR regulation of gene expression by studying rapamycin effect in two hepatic cell lines, the non-tumorigenic WB-F344 cells and the tumorigenic WB311 cells.
Rosa H Jimenez, Ju-Seog Lee, Mirko Francesconi, Gastone Castellani, Nicola Neretti, Jennifer A Sanders, John Sedivy, Philip A Gruppuso   +7 more
doaj   +1 more source

L-myc Gene Expression in Canine Fetal Fibroblasts Promotes Self-Renewal Capacity but Not Tumor Formation

Cells, 2021
Canines are useful in mammalian preclinical studies because they are larger than rodents and share many diseases with humans. Canine fetal fibroblast cells (CFFs) are an easily accessible source of somatic cells.
So Hee Kim, Bokyung Kim, Jung Hak Kim, Dong-Hoon Kim, Seung Hoon Lee, Dong-Seok Lee, Hong J. Lee   +6 more
doaj   +1 more source

PIM1-dependent phosphorylation of Histone H3 at Serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.

, 2007
The serine/threonine kinase PIM1, cooperates with MYC in cell cycle progression and tumorigenesis. However, the nature of this cooperation remains elusive.
Salvatore Oliviero, Serafini, Riccardo, Riccardo Serafini, Alessandra De Robertis, Alessio Zippo, De Robertis, Alessandra, Zippo, Alessio, Oliviero, Salvatore   +7 more
core   +1 more source

MYC-Alarmin Axis As a Novel Oncogenic Driver in a Subgroup of Triple Negative Myeloproliferative Neoplasms

, 2023
Primary Myelofibrosis (PMF) is an aggressive myeloproliferative neoplasm (MPN) characterized by constitutional symptoms, cytopenias, splenomegaly, extramedullary hematopoiesis, bone marrow (BM) fibrosis, and a propensity to transform to acute myeloid ...
Najla H Al Ali (17721657), Dae Hyun Lee (15268276), Parth C Patel (17721660), Siyuan Su (1520791), Daniel Murphy (527711), Rami S Komrokji (17721666), Onyee Chan (17721654), Daesung Lee (10630988), Erika Adriana Eksioglu (17721651), Xiaoqing Yu (86297), Seongseok Yun (3495851), Ling Zhang (18071), Harshani Lawrence (11617009), Rinzine Sammut (17721645), Hai Vu Nguyen (17721648), Andrew T Kuykendall (13810348), Scott H Kaufmann (11548219), Chia-Ho Cheng (108443), Jungwon Moon (17721642), Nicole D Vincelette (17721639), John L Cleveland (17721669), Qianxing Mo (169134), Suzanne Cory (17721663), Shima Nakanishi (15148386), Renan Ferreira (3513698)   +24 more
core   +1 more source