Results 51 to 60 of about 239,792 (215)

Identification of MYC genes in four Cucurbitaceae species and their roles in the response to temperature stress

BMC Genomics
Background Myelocytomatosis (MYC) transcription factors are crucial mediators of the response of plants to environmental stresses through via binding to DNA regulatory regions.
Tao Liu, Yani Zheng, Jingyu Yang, Rourou Li, Huan Chang, Nanyang Li, Wang Suna, Liping Wang, Xing Wang   +8 more
doaj   +1 more source

Striking similarity in the gene expression levels of individual Myc module members among ESCs, EpiSCs, and partial iPSCs. [PDF]

PLoS ONE, 2013
Predominant transcriptional subnetworks called Core, Myc, and PRC modules have been shown to participate in preservation of the pluripotency and self-renewality of embryonic stem cells (ESCs).
Masataka Hirasaki, Keiko Hiraki-Kamon, Masayoshi Kamon, Ayumu Suzuki, Miyuki Katano, Masazumi Nishimoto, Akihiko Okuda   +6 more
doaj   +1 more source

Germinal Centre B Cell Functions and Lymphomagenesis: Circuits Involving MYC and MicroRNAs

Cells, 2019
Background: The transcription factor MYC regulates several biological cellular processes, and its target gene network comprises approximately 15% of all human genes, including microRNAs (miRNAs), that also contribute to MYC regulatory activity.
Marcela Cristina Robaina, Luciano Mazzoccoli, Claudete Esteves Klumb   +2 more
doaj   +1 more source

Integrated analysis of bulk and single-cell RNA-seq reveals the role of MYC signaling in lung adenocarcinoma

Frontiers in Genetics, 2022
MYC is one of the well-known oncogenes, and its important role in cancer still remains largely unknown. We obtained lung adenocarcinoma (LUAD) multi-omics data including genome, transcriptome, and single-cell sequencing data from multiple cohorts.
Lu Hao, Qiuyan Chen, Xi Chen, Qing Zhou
doaj   +1 more source

Hyperthermia inhibits growth of nasopharyngeal carcinoma through degradation of c-Myc

, 2022
Hyperthermia is a widely used adjunct treatment for different cancers including nasopharyngeal carcinoma (NPC). The protooncogene c-Myc is up-regulated in NPC and its expression is associated with poor prognosis. We hypothesized that c-Myc constitutes an
Yongqiang Yang (670525), Wencai Li (3942530), Yingjuan Zheng (12110814), Lei Wang (6656), Xinqiang Li (2554165), Qing Zhang (1802), Xiaole Li (4496476), Daoke Yang (9294902), Shichao Duan (12110811), Rick F. Thorne (11680261)   +9 more
core   +1 more source

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye, Benavente, Sandra Blanco, Elisabete Nascimento, Kurowski, Agata, Nascimento, Elisabete, Hussain, Shobbir, Ilaria Dragoni, Dragoni, Ilaria, Gillich, Astrid, Shobbir Hussain, Sandra Blanco Benavente, Astrid Gillich, Frye, Michaela, Peter Humphreys, Humphreys, Peter, Agata Kurowski   +15 more
core   +1 more source

Cazarin and Derollo et al Figure 3 and Supplemental Figure 3: SHEP N-MYC-ER Phase Set Enrichment Analysis (PSEA) ResultsSource data for MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

, 2023
Source data from Phase Set Enrichment Analysis (PSEA) of oscillating genes from SHEP N-MYC-ER OFF and ON.
Brian J. Altman (16819407), Aalim M. Weljie (244968), Chi V. Dang (9424989), Brian Altman (14202566), Stephano S. Mello (15101894), Rebekah Brooks (16819404), Siti Noor Ain Binti Ahmad Shahidan (16819392), Zandra E. Walton (16819401), Jamison B. Burchett (9707399), Daniel Mwangi (16819395), Rachel E. DeRollo (16819389), Annie L. Hsieh (16819398), Saikumari Krishnaiah (4433761), Juliana Cazarin (16819386), Brian Altman (17117536)   +14 more
core   +1 more source

Transcriptional regulation of prostate kallikrein-like genes by androgen. [PDF]

, 1992
Using gene-specific synthetic oligonucleotides the expression and regulation of kallikrein-like genes in the human prostatic cancer cell line LNCaP were studied.
Schulz, Peter, Fittler, Friedrich, Wolf, Dieter A.   +2 more
core   +1 more source

Cazarin and Derollo et al Figure 3 and Supplemental Figure 3: SKNAS N-MYC-ER Phase Set Enrichment Analysis (PSEA) ResultsSource data for MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

, 2023
 Source data from Phase Set Enrichment Analysis (PSEA) of oscillating genes from SKNAS N-MYC-ER OFF and ON. 
Brian J. Altman (16819407), Aalim M. Weljie (244968), Chi V. Dang (9424989), Brian Altman (14202566), Stephano S. Mello (15101894), Rebekah Brooks (16819404), Siti Noor Ain Binti Ahmad Shahidan (16819392), Zandra E. Walton (16819401), Jamison B. Burchett (9707399), Daniel Mwangi (16819395), Rachel E. DeRollo (16819389), Annie L. Hsieh (16819398), Saikumari Krishnaiah (4433761), Juliana Cazarin (16819386), Brian Altman (17117536)   +14 more
core   +1 more source

Modified screening of MYC promotor region elements using the CRISPR library in ovarian cancer

Journal of Ovarian Research
Ovarian cancer remains one of the most lethal gynecological malignancies owing to its high recurrence rate and chemotherapeutic resistance. MYC is a well-known proto-oncogene that is frequently amplified in ovarian cancer and has been implicated in drug ...
Akiko Yamamoto, Yosuke Tanaka, Sachiko Ishibashi, Masumi Ikeda, Keisuke Sugita, Masanori Ono, Hirotaka Nishi, Morito Kurata   +7 more
doaj   +1 more source