Results 171 to 180 of about 26,095 (198)

Nef mediates neuroimmune response, myelin impairment, and neuronal injury in EcoHIV-infected mice. [PDF]

Life Sci Alliance
Schenck JK, Clarkson-Paredes C, Pushkarsky T, Wang Y, Miller RH, Bukrinsky MI.   +5 more
europepmc   +1 more source

Acute-phase innate immune responses in SIVmac239-infected Mamu-B*08+ Indian rhesus macaques may contribute to the establishment of elite control. [PDF]

Front Immunol
Rosen BC, Sawatzki K, Ricciardi MJ, Smith E, Golez I, Mauter JT, Pedreño-López N, Yrizarry-Medina A, Weisgrau KL, Vosler LJ, Voigt TB, Louw JJ, Tisoncik-Go J, Whitmore LS, Panayiotou C, Ghosh N, Furlott JR, Parks CL, Desrosiers RC, Lifson JD, Rakasz EG, Watkins DI, Gale M.   +22 more
europepmc   +1 more source

RNA splicing patterns contribute to burst size variation among HIV-1-infected Jurkat cell clones. [PDF]

J Virol
Gopal K, Burnett C, Kharytonchyk S, Emery A, Atindaana E, Swanstrom R, Kidd JM, Telesnitsky A.   +7 more
europepmc   +1 more source

Ovarian development is driven by early spatiotemporal priming of the coelomic epithelium

Djari C, Mayère C, Guy M, Perea-Gomez A, Barreau P, Rozier A, Martinez AS, Gibson TJ, Guérin C, Ademi H, Wilhelm D, McKey J, Chaboissier M, Nef S.   +13 more
europepmc   +1 more source

Functional association between the nef gene product and gag-pol region of HIV-1.

Functional association between the nef gene product and gag-pol region of HIV-1.
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Nef Genes of SIV

Journal of Medical Primatology, 1990
Molecular clones of SIVmac were constructed that differed only in sequences within the nef gene. DEAE‐transfection of viral DNA containing an open form of /ic/yiclded virus that replicated with similar kinetics and to a similar extent in macaque peripheral blood lymphocyte (PBL) cultures as virus with a deletion or stop codon within nef. Rhesus monkeys
H W, Kestler, K, Mori, D P, Silva, T, Kodama, N W, King, M D, Daniel, R C, Desrosiers   +6 more
openaire   +2 more sources

Minor nef gene alterations after human HIV-DNA immunisation

AIDS, 2004
Nef gene sequences were analysed in HIV-1-infected patients, immunised with a single nef gene or a combination of nef, rev and tat genes. After three to six immunisations, we found no increase of amino acid substitutions within predicted cytotoxic T-cell epitopes, compared with epitopes located outside predicted sites.
Soo, Aleman, Thomas, Leitner, Margaret A, Liu, Britta, Wahren   +3 more
openaire   +2 more sources

Serological detection of attenuated HIV-1 variants with nef gene deletions

AIDS, 1998
To investigate whether members of a transfusion-linked cohort (the Sydney Bloodbank Cohort) infected with a nef-deleted strain of HIV-1 could be differentiated from individuals infected with wild-type strains of HIV-1 by characterizing the Nef antibody response of cohort members.Retrospective and prospective analysis of the nef gene sequence and the ...
A L, Greenway, J, Mills, D, Rhodes, N J, Deacon, D A, McPhee   +4 more
openaire   +2 more sources

Specificity of anti-Nef antibodies produced in mice immunized with DNA encoding the HIV-1 nef gene product

Vaccine, 1999
Mice immunized with plasmid DNA encoding Nef regulatory protein of human immunodeficiency virus type 1 developed high levels of anti-Nef antibodies. After 4 intramuscular injections of 100 microg plasmid DNA, anti-Nef antibodies reached titers up to 2 x 10(4). A significant specific antibody response was maintained for at least 16 months.
C, Moureau, M, Moynier, V, Kavsan, L, Montagnier, E, Bahraoui   +4 more
openaire   +2 more sources

The nef Gene from a Long-Term HIV Type 1 Nonprogressor

AIDS Research and Human Retroviruses, 1996
We examined the nef gene of HIV-1 in a long-term nonprogressor to look for evidence suggesting an attenuated virus. The nef gene was previously shown to be required for induction of AIDS. Simian immunodeficiency virus (SIV) deleted in nef, while infectious, fails to sustain the high viral loads necessary for the induction of AIDS in infected adult ...
D R, Premkumar, X Z, Ma, R K, Maitra, B K, Chakrabarti, J, Salkowitz, B, Yen-Lieberman, M S, Hirsch, H W, Kestler   +7 more
openaire   +2 more sources