Results 41 to 50 of about 7,394,141 (337)
Genome-wide overexpression screen identifies genes able to bypass p16-mediated senescence in melanoma [PDF]
, 2017 Malignant melanomas often arise from nevi, which result from initial oncogene-induced hyperproliferation of melanocytes that are maintained in a CDKN2A/p16-mediated senescent state.
Stevenson, Alexander J +13 more
core +1 more source
Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein. [PDF]
PLoS ONE, 2013 Breast cancer is one of the most lethal diseases in women; however, the precise etiological factors are still not clear. Genistein (GE), a natural isoflavone found in soybean products, is believed to be a potent chemopreventive agent for breast cancer ...
Yuanyuan Li +3 more
doaj +1 more source
Methylation status of p16 and p14 genes in locally advanced rectal cancer: Potential clinical implication [PDF]
Archives of Biological Sciences, 2018 Methylation of p16 and p14 genes is a common event in colorectal cancers; however, their exact role in the prediction of patients’ outcome is unclear. We conducted this retrospective study to evaluate their potential predictive and/or prognostic roles ...
Kožik Bojana +6 more
doaj +1 more source
Prediction of progression in pTa and pT1 bladder carcinomas with p53, p16 and pRb. [PDF]
, 2004 Currently available prognostic tools appear unable to adequately predict recurrence and progression in non muscle-invasive bladder carcinomas. We aimed to assess the prognostic value of immunohistochemical evaluation of the cell cycle markers p53, p16 ...
S Jordan +11 more
core +1 more source
, 1998 Review on t(4;14)(p16;q32), with data on clinics, and the genes ...
J Bonaventure +3 more
core +1 more source
, 2008 Review on t(2;13)(p16;q12), with data on clinics, and the genes ...
Huret, JL, JL Huret
core +1 more source
Increased Radiosensitivity of p16 Gene‐deleted Human Glioma Cells after Transfection with Wild‐type p16 Gene [PDF]
Japanese Journal of Cancer Research, 1997 The A1235 and T98 cell lines derived from human gliomas have homozygous deletions in their p16 genes and are radiosensitive and radioresistant, respectively, with respect to other established glioma cell lines. These differences in radiosensitivity may be due to variations to some extent among cell lines, rather than genetically defined resistance or ...
Miyakoshi, Junji +5 more
openaire +2 more sources
, 2006 Review on t(4;12)(p16;p13), with data on clinics, and the genes ...
Huret, JL, JL Huret
core +1 more source
Promoter methylation of MLH1, PMS2, MSH2 and p16 is a phenomenon of advanced-stage HCCs. [PDF]
PLoS ONE, 2014 Epigenetic silencing of tumour suppressor genes has been observed in various cancers. Looking at hepatocellular carcinoma (HCC) specific protein silencing was previously demonstrated to be associated with the Hepatitis C virus (HCV).
Inga Hinrichsen +6 more
doaj +1 more source
The Senescence Marker p16Ink4a—A Player of Liver Endothelial Cells Physiology
Biology and Life Sciences Forum, 2023 P16INK4A is a tumor suppressor and cell cycle regulator that has been linked to aging and senescence. In development, a potential role of p21 and of p19ARF has been postulated, but little is known about p16. Our previous results revealed a highly dynamic
Hasan Safwan-Zaiter +2 more
doaj +1 more source