Results 281 to 290 of about 47,513 (307)

[Alterations of the p16 gene for the carcinogenesis in pancreas].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004
Pancreatic cancer is a common malignant neoplasm in digestive tract, which is of unknown etiology as yet. Recent advances in molecular oncology have provided explanations at the DNA level that multiple genetic changes contribute to pancreatic cancer development, in which the p16 locus of tumor tissue is nearly always altered. This tumor suppressor gene,
C, Wang, X, Lu
openaire   +1 more source

[A study on the inactivation of p16 genes and the expression of P16 protein in primary hepatocellular carcinomas].

Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2003
The aim of the present study was to determine whether p16 gene is involved in the genesis of primary hepatocellular carcinoma (HCC). Twenty-five primary HCC tumor and corresponding non-tumor liver tissue specimens were examined for P16 gene alterations.
J, Huang, W, Shen, B, Li, Y, Luo, S, Liao, W, Zhang, N, Cheng   +6 more
openaire   +1 more source

P16 gene in uncultured tumours

Nature, 1994
C H, Spruck, M, Gonzalez-Zulueta, A, Shibata, A R, Simoneau, M F, Lin, F, Gonzales, Y C, Tsai, P A, Jones   +7 more
openaire   +2 more sources

Quantitative Determination of p16 Gene Expression by RT-PCR

2004
In recent years, gene expression quantitation of tumor cells has become of principal importance to analyze gene patterns responsible for cancer development, progression, and resistance to treatment. Whereas semi-quantitative methods, such as Northern blotting analysis, allow only a dichotomous differentiation between positive and negative gene ...
Sylke, Schneider, Kazumi, Uchida, Dennis, Salonga, Ji Min, Yochim, Kathleen D, Danenberg, Peter V, Danenberg   +5 more
openaire   +2 more sources

[Function of p16 gene and correlation of p16 with human cancer].

Sheng li ke xue jin zhan [Progress in physiology], 1998
M, Sun, Y Y, Lu
openaire   +1 more source

High frequency of simultaneous loss of p16 and p16β gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach

Oncogene, 1997
Ralf Metzger, Dennis Salonga, Kathleen Danenberg   +2 more
exaly  

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

Modern Pathology, 2005
Michael Goggins, Scott E Kern, Ralph H Hruban   +2 more
exaly  

Correlation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review

British Journal of Cancer, 2014
Mette Gyldenløve, K Kiss, L Konge
exaly  

Aberrant methylation of p16 INK4a is an early event in lung cancer and a potential biomarker for early diagnosis

Proceedings of the National Academy of Sciences of the United States of America, 1998
Steven A Belinsky, Kristen J Nikula, Geno Saccomanno   +2 more
exaly  

p16/INK4a and p15/INK4b Gene Methylation and Absence of p16/INK4a mRNA and Protein Expression in Burkitt's Lymphoma

Blood, 1998
Kristinn P Magnússon, P Lind, Klas G Wiman   +2 more
exaly