Results 121 to 130 of about 945,913 (292)

Identification of gene expression logical invariants in Arabidopsis. [PDF]

, 2019
Numerous gene expression datasets from diverse tissue samples from the plant variety Arabidopsis thaliana have been already deposited in the public domain. There have been several attempts to do large scale meta-analyses of all of these datasets. Most of
Ball, Bargmann, Barrett, Barrett, Bauer, Birnbaum, Bolstad, Bowman, Brady, Brazma, Carlsbecker, Collin, Craigon, Dalerba, Dalerba, Dalerba, Dinneny, Edgar, Efroni, Harr, He, He, Hubbell, Inlay, Irizarry, Iyer-Pascuzzi, Jakoby, Katari, Kim, Kramer, Lee, Li, Li, Liesecke, Lim, Long, Lukk, Manfield, Montojo, Mutwil, Nawy, Nuccio, Obayashi, Obayashi, Rhee, Rocca-Serra, Sahoo, Sahoo, Sahoo, Sahoo, Sakai, Schmid, Sozzani, Srinivasasainagendra, Swarbreck, Tobias, Toufighi, Van Bel, Volkmer, Yadav, Yadav, Zheng, Zhuo, Zimmermann   +63 more
core   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

A biomarker based on gene expression indicates plant water status in controlled and natural environments

, 2013
Plant or soil water status are required in many scientific fields to understand plant responses to drought. Because the transcriptomic response to abiotic conditions, such as water deficit, reflects plant water status, genomic tools could be used to ...
Blanchet, Nicolas, Boniface, Marie-Claude, Burger, Philippe, Casadebaig, Pierre, Debaeke, Philippe, Langlade, Nicolas B., Marchand, Gwenaëlle, Maury, Pierre, Mayjonade, Baptiste, Nambinina, Fety Andrianasolo, Varès, Didier, Vincourt, Patrick   +11 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates. [PDF]

, 2013
The efficient production of biofuels from cellulosic feedstocks will require the efficient fermentation of the sugars in hydrolyzed plant material.
Arkin, Adam P, Bauer, Stefan, Baumohl, Jason K, Deutschbauer, Adam M, Hazen, Terry, Hu, Ping, Ibáñez, Ana B, Leon, Dacia, Mar, Jordan S, Mitchell, Valerie D, Price, Morgan N, Skerker, Jeffrey M, Tarjan, Daniel R, Wetmore, Kelly M, Wu, Cindy H   +14 more
core   +2 more sources

Divergence and Conservative Evolution of XTNX Genes in Land Plants

Frontiers in Plant Science, 2017
The Toll-interleukin-1 receptor (TIR) and Nucleotide-binding site (NBS) domains are two major components of the TIR-NBS-leucine-rich repeat family plant disease resistance genes.
Yan-Mei Zhang, Jia-Yu Xue, Li-Wei Liu, Xiao-Qin Sun, Guang-Can Zhou, Min Chen, Zhu-Qing Shao, Yue-Yu Hang   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

A basic helix-loop-helix transcription factor, PhFBH4, regulates flower senescence by modulating ethylene biosynthesis pathway in petunia. [PDF]

, 2015
The basic helix-loop-helix (bHLH) transcription factors (TFs) play important roles in regulating multiple biological processes in plants. However, there are few reports about the function of bHLHs in flower senescence.
Bui, Mai, Chang, Xiaoxiao, Jiang, Cai-Zhong, Kasuga, Takao, Reid, Michael S, Yin, Jing   +5 more
core   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Secretory RING finger proteins function as effectors in a grapevine galling insect. [PDF]

, 2019
BackgroundAll eukaryotes share a conserved network of processes regulated by the proteasome and fundamental to growth, development, or perception of the environment, leading to complex but often predictable responses to stress. As a specialized component
Nabity, Paul D, Rispe, Claude, Zhao, Chaoyang   +2 more
core   +3 more sources