Results 251 to 260 of about 211,660 (314)

Clinical Applications of Liquid Biopsy in Colorectal Cancer: A Focus on Registered Clinical Trials. [PDF]

Genes (Basel)
Garcia-Pelaez J, Yáñez Y, Aupí M, Lázaro M, Molero M, Oliver-Tos M, Rausell L, Calabria I.   +7 more
europepmc   +1 more source

Ras oncogene and deregulation of differentiation in thyroid cells

, 2009
Baratta, Maria Giuseppina
core  

Deciphering RTK-RAS and MAPK Pathway Dependencies in Gemcitabine-Treated Pancreatic Ductal Adenocarcinoma Through Conversational Artificial Intelligence. [PDF]

Int J Mol Sci
Diaz FC, Waldrup B, Carranza FG, Manjarrez S, Velazquez-Villarreal E.   +4 more
europepmc   +1 more source

Artesunate directly targeting MMP9 to reduce angiogenesis and increase CD8 + T cell infiltration inhibits hepatocellular carcinoma. [PDF]

Cancer Cell Int
Wang N, Yao L, Dong X, Man X, Liu B, Li H, Sun J, Jiang R, Guo M, Bi J, Wang A.   +10 more
europepmc   +1 more source

Homeobox genes: going for growth

, 2002
Playford, RJ
core  

Targeting Ras Genes in Kidney Disease

Nephron Experimental Nephrology, 2004
Certain changes in cellular function are characteristic of renal disease. Foremost among these is the excessive proliferation of cells, but other phenotypic changes include dysregulated apoptosis, migration, adhesion, contraction, secretion, and receptor expression. Recent advances in cell biology have revealed an extensive role for the small monomeric
Hendry, B M, Sharpe, C C
openaire   +4 more sources

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Extensive sequence homology of the goldfish ras gene to mammalian ras genes

Differentiation, 1986
We cloned ras-related sequences from goldfish genomic libraries constructed as recombinants using the lambda phage. Restriction enzyme mapping of the clones obtained revealed three kinds of ras-related sequences among approximately 350,000 genomic clones. One of these clones was partially sequenced. Comparison with the nucleotide sequences of mammalian
N, Nemoto, K, Kodama, A, Tazawa, P, Masahito, T, Ishikawa   +4 more
openaire   +2 more sources

Ras-like genes and gene families in the mouse

Mammalian Genome, 1991
Four human RAS-like cDNAs and a mouse genomic DNA fragment were used to define novel mouse Ras-like genes and gene families. Inheritance of DNA restriction fragment length variants associated with these genes in recombinant inbred and backcross mice allowed definition of 12 genetic loci, nine of which were mapped, to chromosomes (Chr) 2, 4, 7, 8, 9 ...
G, Drivas, R, Massey, H Y, Chang, M G, Rush, P, D'Eustachio   +4 more
openaire   +2 more sources

Conversion of ras Genes to Cancer Genes

1987
The cellular precursor of Harvey and Balb sarcoma virus, termed proto-ras, from certain tumors registers most frequently as an apparent cancer gene in the gene transfer assay with NIH 3T3 cells [1–4]. The viral ras gene is a dominant transforming gene that elicits all features of oncogenic transformation in a single step upon transfer into established ...
K, Cichutek, P H, Duesberg
openaire   +2 more sources

Incidence of ras gene mutations in neuroblastoma

European Journal of Pediatrics, 1988
Using a rapid dot-blot screening procedure based on DNA amplification and hybridization to synthetic oligonucleotide probes, we investigated 18 neuroblastomas in various clinical stages for the presence of ras mutations. In none of the samples was a mutation in the relevant codons 12, 13 or 61 of Ha-ras, Ki-ras or N-ras found.
K, Ballas, J, Lyons, J W, Janssen, C R, Bartram   +3 more
openaire   +2 more sources