Results 51 to 60 of about 1,074,410 (298)

Deletion of the Transcriptional Regulator MucR in Brucella canis Affects Stress Responses and Bacterial Virulence

Frontiers in Veterinary Science, 2021
The transcriptional regulator MucR is related to normal growth, stress responses and Brucella virulence, and affects the expression of various virulence-related genes in smooth-type Brucella strains.
Jiali Sun, Hao Dong, Hao Dong, Xiaowei Peng, Yufu Liu, Hui Jiang, Yu Feng, Qiaoling Li, Liangquan Zhu, Yuming Qin, Jiabo Ding   +10 more
doaj   +1 more source

Regulation of NF-κB by PML and PML-RARα [PDF]

, 2017
Promyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation.
Ahmed, Abrar, Carmody, Ruaidhri J., Chen, Youhai H., Keeshan, Karen, Lindsay, Andrew J., McCaffrey, Mary W., Mitxitorena, Izaskun, Pandolfi, Pier Paolo, Wan, Xiaochun   +8 more
core   +1 more source

Comparative genome analysis of Wolbachia strain wAu [PDF]

, 2014
BACKGROUND: Wolbachia intracellular bacteria can manipulate the reproduction of their arthropod hosts, including inducing sterility between populations known as cytoplasmic incompatibility (CI). Certain strains have been identified that are unable to
Harris, Simon R., Parkhill, Julian, Sinkins, Steven P., Sutton, Elizabeth R.   +3 more
core   +2 more sources

Outer membrane protein genes and their small non-coding RNA regulator genes in Photorhabdus luminescens

Biology Direct, 2006
Introduction Three major outer membrane protein genes of Escherichia coli, ompF, ompC, and ompA respond to stress factors. Transcripts from these genes are regulated by the small non-coding RNAs micF, micC, and micA, respectively.
Delihas Nicholas, Papamichail Dimitris
doaj   +1 more source

The Escherichia coli transcriptome mostly consists of independently regulated modules [PDF]

, 2019
Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates gene expression. A useful description of the TRN would decompose the transcriptome into targeted effects of individual transcriptional regulators.
A Anand, A Biton, A Delorme, A Frigyesi, A Hyvärinen, A Santos-Zavaleta, A-M Martoglio, AE Teschendorff, B Dalrymple, B Langmead, B-K Cho, B-K Cho, BM Bolstad, C Vijayendran, CL Turnbough Jr, D Kim, D Marbach, D Risso, D-S Huang, DS Latchman, E Nudler, EJ O’Brien, ENCODE Project Consortium., ER Gansner, F Pedregosa, GI Guzmán, GI Guzmán, H Zou, HS Rhee, I Kristoficova, IM Keseler, J Pouyssegur, J Utrilla, JE Galagan, JJ Faith, JM Buescher, JM Engreitz, JM Monk, JT Leek, K Valgepea, K-K Yan, KF Jensen, KJ Karczewski, L Wang, M Ester, M Kim, M Lawrence, M Moretto, M Scott, M Scott, MB Gerstein, MI Love, NE Lewis, O Alter, P Chiappetta, P Comon, PR Subbarayan, PV Phaneuf, R De Smet, R Kolter, RA LaCroix, RB D’agostino, S Gama-Castro, S Lin, SJ Larsen, SW Seo, T Baba, T Barrett, TM Henkin, W Kong, W Liebermeister, W Saelens, X Zhang, Xin Fang, XW Zhang, Y Gao, Y Yamanaka, Z Wang   +77 more
core   +3 more sources

Pluripotency, differentiation, and reprogramming: A gene expression dynamics model with epigenetic feedback regulation [PDF]

, 2015
Characterization of pluripotent states, in which cells can both self-renew and differentiate, and the irreversible loss of pluripotency are important research areas in developmental biology. In particular, an understanding of these processes is essential
Furusawa, Chikara, Kaneko, Kunihiko, Miyamoto, Tadashi   +2 more
core   +9 more sources

Improving gene set enrichment analysis (GSEA) by using regulation directionality

Microbiology Spectrum
To infer the biological meaning from transcriptome data, it is useful to focus on genes that are regulated by the same regulator, i.e., regulons. Unfortunately, current gene set enrichment analysis (GSEA) tools do not consider whether a gene is activated
Biwen Wang, Frans van der Kloet, Mariah B. M. J. Kes, Joen Luirink, Leendert W. Hamoen   +4 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Bacterial nitrate assimilation: gene distribution and regulation [PDF]

, 2011
In the context of the global nitrogen cycle, the importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognized.
Andrew J. Gates, Assumpção, Caballero, Cabello, Chai, Chen, Conrado Moreno-Vivián, David J. Richardson, Flores, Forchhammer, Forchhammer, Gates, Gutierrez, Ishida, Kayumov, Koropatkin, Leigh, Li, Lin, Lledó, Llácer, M. Dolores Roldán, Moreno-Vivián, Nakano, Ogawa, Ohashi, Pawlowski, Paz-Yepes, Pino, Puerta-Fernández, Ramos, Richardson, Sanders, Shao, Shu, Shu, Stuart J. Ferguson, Swanson, Szeto, Toukdarian, Víctor M. Luque-Almagro, Weiss, Weiss, Wray, Wu   +44 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source