Results 71 to 80 of about 2,777,748 (307)

Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network [PDF]

, 2007
Smooth muscle plays a prominent role in many fundamental processes and diseases, yet our understanding of the transcriptional network regulating its development is very limited.
Astorga (Johansson), Jeanette, Jakobsen, Janus S, Astorga, Jeanette,, Carlsson, Peter,, Furlong, E. E., Furlong, Eileen E M, Carlsson, Peter, Gustafson, E. H., Jakobsen, J. S., Braun, M., Gustafson, E Hilary, Karzynski, M., Karzynski, Michal, Sandmann, T., Sandmann, Thomas, Braun, Martina   +15 more
core   +1 more source

In vitro activities of licochalcone A against planktonic cells and biofilm of Enterococcus faecalis

Frontiers in Microbiology, 2022
This study aims to evaluate the in vitro antibacterial and anti-biofilm activities of licochalcone A on Enterococcus faecalis and to investigate the possible target genes of licochalcone A in E. faecalis.
Xiaoju Liu, Xiaoju Liu, Yanpeng Xiong, Yanpeng Xiong, Yiyi Shi, Yiyi Shi, Xiangbin Deng, Xiangbin Deng, Qiwen Deng, Qiwen Deng, Yansong Liu, Yansong Liu, Zhijian Yu, Zhijian Yu, Duoyun Li, Duoyun Li, Jinxin Zheng, Jinxin Zheng, Peiyu Li, Peiyu Li   +19 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Control of relative timing and stoichiometry by a master regulator. [PDF]

PLoS ONE, 2015
Developmental processes in cells require a series of complex steps. Often only a single master regulator activates genes in these different steps. This poses several challenges: some targets need to be ordered temporally, while co-functional targets may ...
Yifat Goldschmidt, Evgeny Yurkovsky, Amit Reif, Roni Rosner, Amit Akiva, Iftach Nachman   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Diversity and functional analysis of LuxR-type transcriptional regulators of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens [PDF]

, 2009
Cyclic lipopeptides (CLPs) are produced by many Pseudomonas species and have several biological functions, including a role in surface motility, biofilm formation, virulence, and antimicrobial activity.
Bruijn, I., de, Raaijmakers, J.M.
core   +1 more source

Attenuation of the sensing capabilities of PhoQ in transition to obligate insect-bacterial association. [PDF]

PLoS Genetics, 2011
Sodalis glossinidius, a maternally inherited endosymbiont of the tsetse fly, maintains genes encoding homologues of the PhoP-PhoQ two-component regulatory system.
Mauricio Henriques Pontes, Kari Lyn Smith, Linda De Vooght, Jan Van Den Abbeele, Colin Dale   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Escherichia coli segments its controls on carbon‐dependent gene expression into global and specific regulations

Microbial Biotechnology, 2021
Summary How bacteria adjust gene expression to cope with variable environments remains open to question. Here, we investigated the way global gene expression changes in E. coli correlated with the metabolism of seven carbon substrates chosen to trigger a
Qing Pan, Zongjin Li, Xian Ju, Chaofan Hou, Yunzhu Xiao, Ruoping Shi, Chunxiang Fu, Antoine Danchin, Conghui You   +8 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source