Results 11 to 20 of about 5,250,240 (290)

Photoacoustic reporter genes for noninvasive molecular imaging and theranostics [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2020
Noninvasive molecular imaging makes the observation and comprehensive understanding of complex biological processes possible. Photoacoustic imaging (PAI) is a fast evolving hybrid imaging technology enabling in vivo imaging with high sensitivity and ...
Zhao Lei   +4 more
doaj   +1 more source

Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter. [PDF]

open access: yesPLoS ONE, 2011
In Drosophila melanogaster the male specific lethal (MSL) complex is required for upregulation of expression of most X-linked genes in males, thereby achieving X chromosome dosage compensation.
Corey Laverty   +3 more
doaj   +1 more source

Generation and Characterization of Recombinant SARS-CoV-2 Expressing Reporter Genes

open access: yesJournal of Virology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes coronavirus disease 2019 (COVID-19), has significantly impacted the human health and economic status worldwide.
Kevin Chiem   +8 more
semanticscholar   +1 more source

Reporter Gene Assays [PDF]

open access: yes, 2009
Reporter gene assays are versatile and sensitive methods of assaying numerous targets in high-throughput drug-screening programs. A variety of reporter genes allow users a choice of signal that can be tailored to the required sensitivity, the available detection apparatus, the cellular system employed, and the required compatibility with multiplexed ...
Liu, A.M.F.   +3 more
openaire   +3 more sources

Environmental Application of Reporter-Genes Based Biosensors for Chemical Contamination Screening

open access: yesArchives of Environmental Protection, 2014
The paper presents results of research concerning possibilities of applications of reporter-genes based microorganisms, including the selective presentation of defects and advantages of different new scientific achievements of methodical solutions in ...
Matejczyk Marzena   +1 more
doaj   +1 more source

Multi-color fluorescent reporter dengue viruses with improved stability for analysis of a multi-virus infection. [PDF]

open access: yesPLoS ONE, 2018
Reporter virus is a versatile tool to visualize and to analyze virus infections. However, for flaviviruses, it is difficult to maintain the inserted reporter genes on the viral genome, limiting its use in several studies that require homogeneous virus ...
Amporn Suphatrakul   +6 more
doaj   +1 more source

Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus

open access: yesMicrobiology Spectrum, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.
Kevin Chiem   +8 more
doaj   +1 more source

Tamoxifen-independent recombination of reporter genes limits lineage tracing and mosaic analysis using CreERT2 lines

open access: yesTransgenic research, 2019
The CreERT2/loxP system is widely used to induce conditional gene deletion in mice. One of the main advantages of the system is that Cre-mediated recombination can be controlled in time through Tamoxifen administration.
Alberto Álvarez-Aznar   +6 more
semanticscholar   +1 more source

Acoustic reporter genes for noninvasive imaging of microbes in mammalian hosts

open access: yesNature, 2017
The mammalian microbiome has many important roles in health and disease, and genetic engineering is enabling the development of microbial therapeutics and diagnostics.
R. Bourdeau   +6 more
semanticscholar   +1 more source

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

open access: yesNature Communications, 2020
Genome-wide association studies (GWAS) have identified ~20 melanoma susceptibility loci, most of which are not functionally characterized. Here we report an approach integrating massively-parallel reporter assays (MPRA) with cell-type-specific epigenome ...
Jiyeon Choi   +26 more
semanticscholar   +1 more source

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