Results 101 to 110 of about 252,546 (355)
Neurogliogenesis and visual system development in "Drosophila" : genetic/genomic analysis of the "Glial cells missing" and "Egghead" genes [PDF]
, 2005 Complex nervous systems are made up by two major cell types, neuronal and glial cell types. A general observation that has been made by lineage analysis of neurogliogenesis in vertebrates and invertebrates is that neurons and glia often share common ...
Fan, Yun
core +1 more source
Progenitor Competence: Genes Switching Places [PDF]
Cell, 2013 Drosophila neural progenitor cells are competent to give rise to certain neuronal cell types only during a limited period of time. Kohwi et al. link the termination of early competence to changes in subnuclear organization of chromatin.
Cayouette, Michel +2 more
openaire +2 more sources
Phenotypic switching in gene regulatory networks [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance Phenotypes of an isogenic cell population are determined by states of low and high gene expression. These are often associated with multiple steady states predicted by deterministic models of gene regulatory networks. Gene expression is, however, regulated via stochastic molecular interactions at transcriptional and translational
Philipp, Thomas +2 more
openaire +2 more sources
Journal of Biological Chemistry, 1982 Immunoglobulin class switch involves a unique recombination event that takes place at the switch (S) region which is located 5' to each constant region (C) gene of the heavy (H) chain.
T. Nikaido +2 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecular Mechanisms Driving Switch Behavior in Xylem Cell Differentiation
Cell Reports, 2019 Summary: Plant xylem cells conduct water and mineral nutrients. Although most plant cells are totipotent, xylem cells are unusual and undergo terminal differentiation.
Gina M. Turco +11 more
doaj +1 more source
In silico analysis of wild-type and mutant KRAS [PDF]
Pharmaciana, 2019 The mutations of the KRAS gene at codons 12, 13, and 61 have been widely reported with different prognosis. In silico is one approach to explain the characteristics of the mutant genes.
Frengki Frengki +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The genetic requirements for fast and slow growth in mycobacteria. [PDF]
PLoS ONE, 2009 Mycobacterium tuberculosis infects a third of the world's population. Primary tuberculosis involving active fast bacterial replication is often followed by asymptomatic latent tuberculosis, which is characterised by slow or non-replicating bacteria ...
Dany J V Beste +5 more
doaj +1 more source