Results 271 to 280 of about 798,219 (310)

The immune NIK1/RPL10/LIMYB signaling module regulates photosynthesis and translation under biotic and abiotic stresses. [PDF]

Nat Commun
Ferreira MA, Teixeira RM, Brustolini OJB, Saia TFF, Jean-Baptiste J, Ribeiro NGA, Breves SS, Sampaio FR, Santos EGD, Leon BA, Oliveira CC, Duarte CEM, Lima LL, Oliveira LL, Ramos HJO, Reis PAB, Fontes EPB.   +16 more
europepmc   +1 more source

Multi-omics analysis reveals that Bacillus spp. enhance mucosal antiviral immunity in teleost fish by mediating diglyceride production through lipid metabolism. [PDF]

Microbiome
Cheng G, Kong W, Lin R, Jiang Z, Wang X, Qin X, Shi Y, Yang P, Chen X, Xia L, Xu Z.   +10 more
europepmc   +1 more source

Deletion of the Human Cytomegalovirus US2 to US11 Gene Family Members Impairs the Type-I Interferon Response. [PDF]

Viruses
Penner I, Krämer N, Hirsch J, Büscher N, Schmidt H, Plachter B.   +5 more
europepmc   +1 more source

Genomic evidence of the blood virome and bacteriome provides insights into prevalence, evolution, and susceptibility-related genes across Eurasian pigs. [PDF]

BMC Genomics
Liu Z, Lu SY, Ma SJ, Zhou L, Li WY, Du H, Liu JF.   +6 more
europepmc   +1 more source

Haspin kinase inhibition dampens pseudorabies virus infection <i>in vitro</i>. [PDF]

Front Vet Sci
Tan L, Yang Y, Huang X, Yuan Y, Wang K, Peng X, He Y, Wang Y, Lei L, Chen Y, Duan D, Wang N, Yang Y, Dai F, Huang C, Wang A.   +15 more
europepmc   +1 more source

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Viral gene therapy

Clinical and Translational Oncology, 2006
Cancer is a multigenic disorder involving mutations of both tumor suppressor genes and oncogenes. A large body of preclinical data, however, has suggested that cancer growth can be arrested or reversed by treatment with gene transfer vectors that carry a single growth inhibitory or pro-apoptotic gene or a gene that can recruit immune responses against ...
Pablo Mancheño-Corvo, Pilar Martin-Duque   +1 more
openaire   +3 more sources

Viral vectors for gene therapy

Trends in Biotechnology, 1998
Gene therapy is now being applied to the treatment of wide variety of acquired and inherited diseases. One of the rate-limiting steps for successful gene therapy is the efficiency of gene transfer. A number of different viral systems are being developed for use as vectors for ex vivo and in vivo gene transfer, including retroviruses, adenoviruses ...
Steven C. Ghivizzani, Hideaki Tahara, Paul D. Robbins   +2 more
openaire   +6 more sources

Sequencing of Viral Genes

2009
The use of molecular techniques in epidemiology gives a better understanding of viral transmission and diversity, and helps to define and characterizc outbreaks. By elucidating transmission patterns and defining outbreak parameters, appropriate preventive measures can be implemented in a timely fashion.
Kirsti Vainio, Carol Holm-Hansen
openaire   +3 more sources

Viral gene delivery

Expert Opinion on Investigational Drugs, 1999
Experimental studies of viral gene delivery generally support the principle that virus-mediated gene transfer is indeed possible. However, the field of gene therapy has not yet been realised as a practicable clinical intervention. The delay in translation of laboratory work to clinical utility largely reflects the inability of gene delivery vectors to ...
openaire   +2 more sources

Gene Therapy with Viral Vectors

Annual Review of Pharmacology and Toxicology, 2003
A key factor in the success of gene therapy is the development of gene delivery systems that are capable of efficient gene transfer in a broad variety of tissues, without causing any pathogenic effect. Currently, viral vectors based on many different viruses have been developed, and their performance and pathogenicity has been evaluated in animal ...
Inder M. Verma, Neeltje A. Kootstra
openaire   +3 more sources