The evolution of superbugs in space: a genomic perspective on pathogens in the International Space Station environment [PDF]
Journal of Genetic Engineering and BiotechnologyMicrogravity, pressure, and temperature variations in the International Space Station (ISS) create conditions leading to the emergence of superbugs.
Sara Pearl +5 more
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Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function [PDF]
Stem Cell Reports, 2019 Summary: With extended stays aboard the International Space Station (ISS) becoming commonplace, there is a need to better understand the effects of microgravity on cardiac function.
Alexa Wnorowski +12 more
doaj +3 more sources
The immunosurveillance signature predicts the prognosis and immunotherapy sensitivity for colon adenocarcinoma [PDF]
Scientific ReportsColon adenocarcinoma (COAD) is a leading cause of cancer-related mortality worldwide, with immune escape being a significant factor in the failure of immunotherapy.
Yan Xiong +7 more
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Molecular identification of pathogenic Escherichia coli virulence genes and histopathological analysis in chickens condemned for airsacculitis [PDF]
Ciência Rural, 2023 : The present study identified virulence genes and pathological changes caused by Escherichia coli in chicken carcasses condemned for airsacculitis and assessed if the histopathological examination and polymerase chain reaction (PCR) were effective for ...
Mylla Christy da Silva Dufossé +6 more
doaj +1 more source
Animals, 2022 Escherichia coli infections are a major problem in modern poultry production. Avian pathogenic E. coli (APEC) strains have several mechanisms that enable them to colonize various ecosystems. In this study, 290 E.
Jarosław Wilczyński +3 more
doaj +1 more source
npj Microgravity, 2023 Efficient generation of cardiomyocytes from human-induced pluripotent stem cells (hiPSCs) is important for their application in basic and translational studies. Space microgravity can significantly change cell activities and function.
Hyun Hwang +7 more
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Characterization of metagenome-assembled genomes from the International Space Station
Microbiome, 2023 Background Several investigations on the microbial diversity and functional properties of the International Space Station (ISS) environment were carried out to understand the influence of spaceflight conditions on the microbial population.
Nitin K. Singh +6 more
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Insertion sequence contributes to the evolution and environmental adaptation of Acidithiobacillus
BMC Genomics, 2023 Background The genus Acidithiobacillus has been widely concerned due to its superior survival and oxidation ability in acid mine drainage (AMD). However, the contribution of insertion sequence (IS) to their biological evolution and environmental ...
Shanshan Huang +9 more
doaj +1 more source
Human mesenchymal stem cell responses to hydrostatic pressure and shear stress [PDF]
European Cells & Materials, 2016 The effects of mechanical stimuli to which cells are exposed in vivo are, at best, incompletely understood; in this respect, gene-level information regarding cell functions which are pertinent to new tissue formation is of special interest and importance
P Becquart +8 more
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Correlation Between the Transcriptional Level of iss and bor Virulence Genes of Avian Pathogenic Escherichia Coli O78 Inoculated to Chicken Serum [PDF]
Iranian Journal of Veterinary Medicine, 2021 BACKGROUND: Blue Open Reading (bor) and increased serum survival (iss) genes, with intense structural and possible functional similarities, engage in the serum resistance of Avian Pathogenic Escherichia coli O78 (APEC-O78).
Somaye Abbasi +3 more
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