Results 1 to 10 of about 2,761,484 (346)

Association analysis of Epworth Sleepiness Scale (ESS) scores with serotonin transporter (5-HTT- LPR, 5-HTT-VNTR) and circadian (PER3-VNTR) genes [PDF]

Sleep Science
Excessive daytime sleepiness (EDS) is a common complaint encountered in clinical practice with serious consequences both for individual and society since it can increase the ratio of motor vehicle accidents, work- related incidents, and deaths. Moreover,
Filiz Ozen, Zeynep Yegin, Zuhal Aydan Saglam, Figen Yavlal, Haydar Koc, Celal Ulasoglu   +5 more
doaj   +1 more source

Network assisted analysis to reveal the genetic basis of autism

, 2015
While studies show that autism is highly heritable, the nature of the genetic basis of this disorder remains illusive. Based on the idea that highly correlated genes are functionally interrelated and more likely to affect risk, we develop a novel ...
Lei, Jing, Liu, Li, Roeder, Kathryn
core   +1 more source

Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project [PDF]

, 2018
Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment.
Abramson, Lior, Almqvist, Catarina, Bartels, Meike, Bayasgalan, Gombojav, Bjerregaard-Andersen, Morten, Boivin, Michel, Boomsma, Dorret I, Brandt, Ingunn, Brendgen, Mara, Brescianini, Sonia, Burt, S Alexandra, Corley, Robin P, Craig, Jeffrey M, Cutler, Tessa L, Derom, Catherine, Dionne, Ginette, Dubois, Lise, Fagnani, Corrado, Fisher, Abigail, Harris, Jennifer R, Haworth, Claire MA, Heikkila, Kauko, Hopper, John L, Huibregtse, Brooke M, Hur, Yoon-Mi, Jelenkovic, Aline, Ji, Fuling, Kaprio, Jaakko, Kim, Jina, Klump, Kelly L, Knafo-Noam, Ariel, Krueger, Robert F, Lee, Jooyeon, Lee, Sooji, Llewellyn, Clare H, Loos, Ruth JF, Magnusson, Patrik KE, Mankuta, David, McGue, Matt, Narandalai, Danshiitsoodol, Nelson, Tracy L, Nielsen, Henning Beck, Nilsen, Thomas Sevenius, Ning, Feng, Ooki, Syuichi, Pahlen, Shandell, Pang, Zengchang, Pietilainen, Kirsi H, Plomin, Robert, Rasmussen, Finn, Rebato, Esther, Saffery, Richard, Saudino, Kimberly J, Silventoinen, Karri, Sodemann, Morten, Sorensen, Thorkild IA, Stazi, Maria A, Sund, Reijo, Sung, Joohon, Tarnoki, Adam D, Tarnoki, David L, Tynelius, Per, Ullemar, Vilhelmina, van Beijsterveld, Catharina EM, Vitaro, Frank, Vlietinck, Robert F, Whitfield, Keith E, Willemsen, Gonneke, Yokoyama, Yoshie   +68 more
core   +6 more sources

Exploring genetic associations of Crohn’s disease and ulcerative colitis with extraintestinal cancers in European and East Asian populations

Frontiers in Immunology
BackgroundPrevious studies have reported associations of Crohn’s disease (CD) and ulcerative colitis (UC) with the risks of extraintestinal cancers, but the causality remains unclear.MethodsUsing genetic variations robustly associated with CD and UC ...
Chengdong Yu, Jiawei Xu, Siyi Xu, Lei Tang, Qinyuan Han, Xiaoqiang Zeng, Yanxiao Huang, Tenghua Yu, Zhengkui Sun   +8 more
doaj   +1 more source

Genetic association studies [PDF]

Neurology, 2001
The urge to associate genetic markers with human traits or diseases has been around for centuries. The association of specific hair colors with certain personality types has a long tradition in folklore. The rate-limiting factor has been the availability of measurable genetic markers.
Thomas D. Bird, Gail P. Jarvik, Nicholas W. Wood   +2 more
openaire   +1 more source

Coincident onset of multiple sclerosis and herpes simplex virus 1 encephalitis. a case report [PDF]

, 2017
Background: Along with vitamin D, smoking, body mass index and others, Epstein Barr virus, other herpesviruses and human endogenous retroviruses represent plausible environmental risk factors for multiple sclerosis.
Buscarinu, M. C., Ferraldeschi, Michela, Fornasiero, Arianna, Renie', Roberta, Ristori, Giovanni, Romano, Silvia, Salvetti, Marco, Trasimeni, Guido   +7 more
core   +2 more sources

Sepsis genomics: Stepping forward toward sepsis prevention?

International Journal of Advanced Medical and Health Research, 2014
The era of personalized medicine has already begun and now it is time to initiate personalized prevention strategies against diseases. Infectious diseases have a higher mortality than any other illness, especially in developing countries.
Benet Bosco Dhas, Hiasindh Ashmi, Ballambattu Vishnu Bhat   +2 more
doaj   +1 more source

Bayesian Model Comparison in Genetic Association Analysis: Linear Mixed Modeling and SNP Set Testing [PDF]

, 2015
We consider the problems of hypothesis testing and model comparison under a flexible Bayesian linear regression model whose formulation is closely connected with the linear mixed effect model and the parametric models for SNP set analysis in genetic ...
Wen, Xiaoquan
core  

Efficient inference for genetic association studies with multiple outcomes

, 2017
Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study.
Davison, Anthony C., Hager, Jörg, Irincheeva, Irina, Ruffieux, Hélène   +3 more
core   +1 more source

Genetically determined height and coronary artery disease. [PDF]

, 2015
BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear.
Amouyel, P., Anand, S., Assimes, T. L., Blankenberg, S., Boehm, B. O., Burgess, S., Clarke, R. J., Collins, R., Danesh, J., Dedoussis, G., Deloukas, P., Erdmann, J., Farrall, M., Franks, Paul,, Groop, Leif,, Hall, A. S., Hamby, S. E., Hamsten, A., Hengstenberg, C., Hopewell, J. C., Hovingh, G. Kees, Ingelsson, E., Kanoni, S., Kathiresan, S., Kee, F., Koenig, I. R., Kooner, J., Lehtimaeki, T., Lund University., Lund University., Lund University., Lund University., Maerz, W., McPherson, R., Metspalu, A., Nelson, C. P., Nieminen, M. S., O'Donnell, C. J., Palmer, C. N. A., Perola, M., Peters, A., Reilly, M. P., Ripatti, S., Roberts, R., Saleheen, D., Salomaa, V., Samani, N. J., Schreiber, S., Schunkert, H., Shah, S. H., Siegbahn, A., Thompson, J. R., Thorsteinsdottir, U., Veronesi, G., Wareham, N., Watkins, H., Willenborg, C., Willer, C. J., Zalloua, P. A., Zeng, L.   +59 more
core   +5 more sources