Results 31 to 40 of about 8,825,337 (378)

Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control

open access: yesBMC Research Notes, 2018
Objective Clinical research on gene therapy has advanced the field of veterinary medicine, and gene doping, which is the illegal use of gene therapy, has become a major concern in horseracing. Since the International Federation of Horseracing Authorities
Teruaki Tozaki   +8 more
doaj   +1 more source

Genetic association studies in Thorax [PDF]

open access: yesThorax, 2005
A guide to assessing the validity of genetic association studies in respiratory disease Increasing knowledge regarding the extent of genetic variation in the human genome has led to an explosion of interest in performing genetic association studies in complex diseases.
John D Blakey, Ian P. Hall
openaire   +2 more sources

Genetic components in diabetic retinopathy

open access: yesIndian Journal of Ophthalmology, 2016
Diabetic retinopathy (DR) is a serious complication of diabetes, which is fast reaching epidemic proportions worldwide. While tight glycemic control remains the standard of care for preventing the progression of DR, better insights into DR etiology ...
Bibhudatta Mishra   +2 more
doaj   +1 more source

The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]

open access: yes, 2013
Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel   +12 more
core   +2 more sources

Progress in Genetic Studies of Tourette’s Syndrome

open access: yesBrain Sciences, 2017
Tourette’s Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time.
Yanjie Qi   +3 more
doaj   +1 more source

PsychArray-Based Genome Wide Association Study of Suicidal Deaths in India

open access: yesBrain Sciences, 2023
Background: Suicide is a preventable but escalating global health crisis. Genome-wide association studies (GWAS) studies to date have been limited, and some are underpowered.
Chittaranjan Behera   +6 more
doaj   +1 more source

Modeling and Testing for Joint Association Using a Genetic Random Field Model [PDF]

open access: yes, 2014
Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown.
Adler   +24 more
core   +2 more sources

Genetic Association Studies [PDF]

open access: yesCirculation, 2008
With the completion of the HapMap project1 and the development of technology that allows the examination of ≥1 million genetic polymorphisms at once, genetic association studies are becoming more comprehensive. This article first provides a brief overview of the rationale for genetic association studies; it then discusses the primary features ...
openaire   +2 more sources

Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations

open access: yesFrontiers in Genetics, 2019
Background: Esophageal squamous cell carcinoma (ESCC), one of the most aggressive cancers, is endemic in Sub-Saharan Africa, constituting a major health burden.
Hannah Simba   +8 more
doaj   +1 more source

Analysis of the association between rs12917707 and rs11864909 single nucleotide polymorphisms in the region of the uromoduline gene and chronic kidney disease – a family-based study

open access: yesAnnals of Agricultural and Environmental Medicine, 2017
Chronic kidney disease (CKD) is an important challange for healthcare systems wordwide because of its high prevalence and serious late complications.
Joanna Żywiec   +3 more
doaj   +1 more source

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