Results 41 to 50 of about 8,691,632 (395)

Bayesian Multi-SNP Genetic Association Analysis: Control of FDR and Use of Summary Statistics

open access: yesbioRxiv, 2018
Multi-SNP genetic association analysis has become increasingly important in analyzing data from genome-wide association studies (GWASs) and molecular quantitative trait loci (QTL) mapping studies.
Yeji Lee   +3 more
semanticscholar   +1 more source

Conservation of Animal Genetic Resources in the Danubian Valley

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The overall aim of gene conservation is the preservation of animal genetic resources (AnGR). Since the well balanced, diverse and healthy supply of food is a major element of the national food sovereignty, hence successful animal production is not ...
Pal Hajas
doaj  

Sepsis genomics: Stepping forward toward sepsis prevention?

open access: yesInternational Journal of Advanced Medical and Health Research, 2014
The era of personalized medicine has already begun and now it is time to initiate personalized prevention strategies against diseases. Infectious diseases have a higher mortality than any other illness, especially in developing countries.
Benet Bosco Dhas   +2 more
doaj   +1 more source

A review of kernel methods for genetic association studies

open access: yesGenetic Epidemiology, 2019
Evaluating the association of multiple genetic variants with a trait of interest by use of kernel‐based methods has made a significant impact on how genetic association analyses are conducted. An advantage of kernel methods is that they tend to be robust
N. Larson, Jun Chen, D. Schaid
semanticscholar   +1 more source

The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]

open access: yes, 2013
Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel   +12 more
core   +2 more sources

Evaluation of the Association of Htr2a Gene Rs6313 Polymorphism with Heroin Dependence in a Sample from Northwest Iran

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Heroin dependence is a chronic relapsing disorder caused by a combination of genetic, epigenetic, and environmental factors. The genetic contribution in the vulnerability to heroin dependence is 40%-60%. Alterations in dopamine transport in
Fatemeh Mahmoudi   +3 more
doaj  

Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children

open access: yesHuman Genomics, 2011
Type 2 diabetes represents an increasing health burden. Its prevalence is rising among younger age groups and differs among racial/ethnic groups. Little is known about its genetic basis, including whether there is a genetic basis for racial/ethnic ...
Klimentidis Yann C   +5 more
doaj   +1 more source

Sex Differences in Genetic Associations With Longevity [PDF]

open access: yesJAMA Network Open, 2018
Sex differences in genetic associations with human longevity remain largely unknown; investigations on this topic are important for individualized health care.To explore sex differences in genetic associations with longevity.This population-based case-control study used sex-specific genome-wide association study and polygenic risk score (PRS) analyses ...
Jichun Xie   +43 more
openaire   +9 more sources

MetaGenyo: a web tool for meta-analysis of genetic association studies

open access: yesBMC Bioinformatics, 2017
Genetic association studies (GAS) aims to evaluate the association between genetic variants and phenotypes. In the last few years, the number of this type of study has increased exponentially, but the results are not always reproducible due to ...
Jordi Martorell-Marugán   +3 more
semanticscholar   +1 more source

Modeling and Testing for Joint Association Using a Genetic Random Field Model [PDF]

open access: yes, 2014
Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown.
Adler   +24 more
core   +2 more sources

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