Results 41 to 50 of about 7,627,088 (344)

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Causal effect of polyunsaturated fatty acids on bone mineral density and fracture

Frontiers in Nutrition, 2022
BackgroundPolyunsaturated fatty acids (PUFAs) are closely related to osteoporosis. To test their causal relationship, we conducted a Mendelian randomization (MR) analysis.MethodsWe analyzed the causal relationship between four PUFAs measures, n-3 PUFAs ...
Sha-Sha Tao, Sha-Sha Tao, Sha-Sha Tao, Peng Wang, Xin-Yi Wang, Xin-Yi Wang, Kang-Jia Yin, Kang-Jia Yin, Xiao-Ke Yang, Zhi-Xin Wang, De-Guang Wang, Hai-Feng Pan, Hai-Feng Pan   +12 more
doaj   +1 more source

Genetic association studies [PDF]

Neurology, 2001
The urge to associate genetic markers with human traits or diseases has been around for centuries. The association of specific hair colors with certain personality types has a long tradition in folklore. The rate-limiting factor has been the availability of measurable genetic markers.
Thomas D. Bird, Gail P. Jarvik, Nicholas W. Wood   +2 more
openaire   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Age and sex differences in the association between APOE genotype and Alzheimer’s disease in a Taiwan Chinese population

Frontiers in Aging Neuroscience, 2023
IntroductionThe Apolipoprotein E (APOE) epsilon (ε) 4 allele is a well-established risk factor for late-onset Alzheimer’s disease (AD). Reports on white ancestry populations have showed that age, sex, and ethnicity have different effects on the ...
Ling-Chun Huang, Ling-Chun Huang, Ling-Chun Huang, Mei-Yueh Lee, Mei-Yueh Lee, Ching-Fang Chien, Ching-Fang Chien, Ching-Fang Chien, Yang-Pei Chang, Yang-Pei Chang, Yang-Pei Chang, Kuan-Ying Li, Kuan-Ying Li, Kuan-Ying Li, Yuan-Han Yang, Yuan-Han Yang, Yuan-Han Yang, Yuan-Han Yang   +17 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Genetic Association Studies [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2002
The widespread availability of DNA from large population studies, the development of rapid throughput genotyping assays, and the identification of numerous polymorphisms in genes of interest make it easier to perform genetic association studies in humans. We consider these studies appropriate areas of research in relation to atherosclerosis, thrombosis,
openaire   +3 more sources

Understanding molecular mechanisms of vertebral number of variations on Mongolian sheep using candidate genes analysis [PDF]

Animal Bioscience
Objective This study aimed to investigate the genetic link between variations in vertebral number and meat production traits, such as body weight and body measurements (body length, body height, heart girth, and shin width) in Mongolian (Bayantsagaan ...
Chimgee Purev, Huiguang Wu, Khosbayar Lkhagva, Odbayar Tumendemberel   +3 more
doaj   +1 more source

Schizophrenia plausible protective effect of microRNA-137 is potentially related to estrogen and prolactin in female patients

Frontiers in Psychiatry, 2023
BackgroundSchizophrenia (SCZ) is a serious chronic mental disorder. Our previous case–control genetic association study has shown that microRNA-137 (miR-137) may only protect females against SCZ.
Qian Peng, Zhun Dai, Jingwen Yin, Dong Lv, Xudong Luo, Susu Xiong, Zhijiang Yang, Guangmin Chen, Yaxue Wei, Ying Wang, Dandan Zhang, Lulu Wang, Debo Yu, Yusheng Zhao, Dele Lin, Zhiyu Liao, Yongxi Zhong, Zhixiong Lin, Juda Lin   +18 more
doaj   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source