Results 11 to 20 of about 2,429,135 (273)
Genetic model misspecification in genetic association studies [PDF]
BMC Research Notes, 2017 Objective The underlying model of the genetic determinant of a trait is generally not known with certainty a priori. Hence, in genetic association studies, a dominant model might be erroneously modelled as additive, an error investigated previously.
Amadou Gaye, Sharon K. Davis
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ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis [PDF]
G3: Genes, Genomes, Genetics, 2016 Meta-analysis has become a popular tool for genetic association studies to combine different genetic studies. A key challenge in meta-analysis is heterogeneity, or the differences in effect sizes between studies.
Eun Yong Kang +5 more
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Linear regression in genetic association studies. [PDF]
PLoS ONE, 2013 In genomic research phenotype transformations are commonly used as a straightforward way to reach normality of the model outcome. Many researchers still believe it to be necessary for proper inference. Using regression simulations, we show that phenotype
Petra Bůžková
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Reporting and evaluating genetic association studies [PDF]
Respiratory Research, 2009 Genetic association studies have become an important part of our scientific landscape. This commentary discusses some basic scientific issues which should be considered when reporting and evaluating such studies including SNP Discovery, Genotyping and ...
Peters Stephen P
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Screening properties of trend tests in genetic association studies [PDF]
Scientific Reports, 2023 In genome-wide association study, extracting disease-associated genetic variants among millions of single nucleotide polymorphisms is of great importance.
Zhenzhen Jiang +2 more
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Editorial: Genetic association studies in oil seeds [PDF]
Frontiers in GeneticsV. G. Shobhana +3 more
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Genetic Determinants of Premature Menopause in A Mashhad Population Cohort [PDF]
International Journal of Fertility and Sterility, 2021 Background: Premature menopause is characterized by amenorrhea before age of 40 years, markedly raised serumluteinizing hormone (LH) level, follicle-stimulating hormone (FSH) level and reduced serum level of estradiol.Genome-wide analysis suggested ...
Mohammad Reza Mirinezhad +9 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 The aim of this study was to evaluate tumor necrosis factor alpha (TNF-α), interleukin (IL)- 17A/F levels in the serum of ankylosing spondylitis (AS) patients after anti-TNF therapy, in order to understand how these cytokines are involved in this ...
Fernanda Formaggi Lara-Armi +7 more
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Population stratification and genetic association studies in South Asia [PDF]
, 2005 Population stratification and its influence on genetic association studies is a controversial topic. Although it has been suggested that stratification is unlikely to bias the results of association studies conducted in developed countries, convincing ...
Bittles, A.H.
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Anais Brasileiros de Dermatologia, 2014 Vitiligo is a chronic stigmatizing disease, already known for millennia, which mainly affects melanocytes from epidermis basal layer, leading to the development of hypochromic and achromic patches. Its estimated prevalence is 0.5% worldwide.
Roberto Gomes Tarlé +3 more
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