Results 21 to 30 of about 2,429,135 (273)
Frontiers in Cardiovascular Medicine, 2023 HIV-associated lipodystrophy (HIVLD) is a metabolic condition with an irregularity in the production of lipoprotein particles, and its occurrence varies among HIV-infected patients. MTP and ABCG2 genes have a role in the transport of lipoproteins.
HariOm Singh +12 more
doaj +1 more source
Multiple Group Testing Procedures for Analysis of High-Dimensional Genomic Data [PDF]
Genomics & Informatics, 2016 In genetic association studies with high-dimensional genomic data, multiple group testing procedures are often required in order to identify disease/trait-related genes or genetic regions, where multiple genetic sites or variants are located within the ...
Hyoseok Ko, Kipoong Kim, Hokeun Sun
doaj +1 more source
Genetic Association Studies [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 The widespread availability of DNA from large population studies, the development of rapid throughput genotyping assays, and the identification of numerous polymorphisms in genes of interest make it easier to perform genetic association studies in humans. We consider these studies appropriate areas of research in relation to atherosclerosis, thrombosis,
openaire +3 more sources
Stroke Genetics: A Review and Update [PDF]
Journal of Stroke, 2014 Stroke genetics includes several topics of clinical interest, including (1) molecular genetic variations affecting risk of monogenic stroke syndromes; (2) molecular genetic variations affecting risk of common stroke syndromes, sometimes with specific ...
Arne Lindgren
doaj +1 more source
Genetic association studies [PDF]
Neurology, 2001 The urge to associate genetic markers with human traits or diseases has been around for centuries. The association of specific hair colors with certain personality types has a long tradition in folklore. The rate-limiting factor has been the availability of measurable genetic markers.
Thomas D. Bird +2 more
openaire +1 more source
An inferential study of the phenotype for the chromosome 15q24 microdeletion syndrome: a bootstrap analysis [PDF]
PeerJ, 2016 In January 2012, a review of the cases of chromosome 15q24 microdeletion syndrome was published. However, this study did not include inferential statistics.
Antonio Palazón-Bru +4 more
doaj +2 more sources
Assessment of Saffron Neuroprotective Properties in Rat Retina versus Light Damage [PDF]
Research Journal of Pharmacognosy, 2020 Background and objectives: Crocus sativus L. (Iridaceae) commonly known as saffron, is a popular spice which is used for its pleasant aroma and favored color.
Nayebali Ahmadi +7 more
doaj +1 more source
Genetic variants related to physical activity or sedentary behaviour: a systematic review
International Journal of Behavioral Nutrition and Physical Activity, 2021 Background Research shows that part of the variation in physical activity and sedentary behaviour may be explained by genetic factors. Identifying genetic variants associated with physical activity and sedentary behaviour can improve causal inference in ...
Lene Aasdahl +7 more
doaj +1 more source
Genetic Association Studies [PDF]
Circulation, 2008 With the completion of the HapMap project1 and the development of technology that allows the examination of ≥1 million genetic polymorphisms at once, genetic association studies are becoming more comprehensive. This article first provides a brief overview of the rationale for genetic association studies; it then discusses the primary features ...
openaire +2 more sources
Population Structure and Cryptic Relatedness in Genetic Association Studies [PDF]
, 2009 We review the problem of confounding in genetic association studies, which arises principally because of population structure and cryptic relatedness. Many treatments of the problem consider only a simple ``island'' model of population structure. We take
Astle, William, Balding, David J.
core +4 more sources