Results 1 to 10 of about 931,040 (332)
Journal of biological physics, 2001 New developments are presented in the framework of the model introduced by the authors in refs. [1,2] and in which nucleotides as well as codons are classified in crystal bases of the quantum group U_q(sl(2)+sl(2)) in the limit q -> 0. An operator which gives the correspondence between the amino-acids and the codons is now obtained for any known ...
L. Frappat, A. Sciarrino, P. Sorba
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Scientific Reports, 2023 The ubiquitin‒proteasome system (UPS) and autophagy are the two primary cellular pathways of misfolded or damaged protein degradation that maintain cellular proteostasis.
Atsushi Hatanaka +9 more
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Evolution of the genetic code [PDF]
Transcription, 2021 Diverse models have been advanced for the evolution of the genetic code. Here, models for tRNA, aminoacyl-tRNA synthetase (aaRS) and genetic code evolution were combined with an understanding of EF-Tu suppression of tRNA 3rd anticodon position wobbling.
Lei Lei, Zachary Frome Burton
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Journal of Diabetes Research, 2021 Type 1 diabetes (T1D) is an autoimmune disease that culminates in beta cell destruction in the pancreas and, subsequently, deficiency in insulin production.
Tatiane M. Preisser +6 more
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A computational screen for alternative genetic codes in over 250,000 genomes
eLife, 2021 The genetic code has been proposed to be a ‘frozen accident,’ but the discovery of alternative genetic codes over the past four decades has shown that it can evolve to some degree.
Yekaterina Shulgina, Sean R Eddy
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Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems
Frontiers in Genetics, 2022 Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their cognate tRNAs and acylate them with one of the proteinogenic amino acids.
Takahito Mukai +7 more
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Mistranslation of the genetic code [PDF]
FEBS Letters, 2014 During mRNA decoding at the ribosome, deviations from stringent codon identity, or “mistranslation,” are generally deleterious and infrequent. Observations of organisms that decode some codons ambiguously, and the discovery of a compensatory increase in mistranslation frequency to combat environmental stress have changed the way we view “errors” in ...
Moghal, Adil +2 more
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Special identity subgraph in genetic code [PDF]
Network Biology, 2022 The genetic code is a series of codons that stores genetic information about protein molecule formation. The identity graph of a group G is a graph in which the vertex set is the set of all elements of the group and two vertices in G are adjacent if a.b =
Birinchi Kumar Boruah, Tazid Ali
doaj
Frontiers in Bioengineering and Biotechnology, 2022 Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of
Ragunathan Bava Ganesh +1 more
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On the origin of the genetic code [PDF]
FEBS Letters, 1994 A series of stages in the evolution of the genetic code is postulated, representing a chain of logical steps that leads to the present‐day code. The stages described are based on translation machinery between the RNA world and that of amino acids, a model that consists of an RNA assembler strand along which RNA hairpin molecules are lined up, forming a
Hans Kuhn, Jürg Waser
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