Results 21 to 30 of about 931,040 (332)

DNA as classical and quantum information system: Implication to gene expression in normal and cancer cells [PDF]

Archive of Oncology, 2005
Usually, we think about DNA as a molecular machinery system responsible to make proteins. Protein looks like a second side of DNA code because mapping function is based on a classical information system (chemical/physical) by code 43=64.
Koruga Ðuro
doaj   +1 more source

A Realistic Model under which the Genetic Code is Optimal [PDF]

, 2013
The genetic code has a high level of error robustness. Using values of hydrophobicity scales as a proxy for amino acid character, and the Mean Square measure as a function quantifying error robustness, a value can be obtained for a genetic code which ...
Buhrman, Harry, Klau, Gunnar W., Schaffner, Christian, Speijer, Dave, Stougie, Leen, van der Gulik, Peter T. S.   +5 more
core   +5 more sources

A discriminator code–based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteria

eLife, 2018
D-aminoacyl-tRNA deacylase (DTD) acts on achiral glycine, in addition to D-amino acids, attached to tRNA. We have recently shown that this activity enables DTD to clear non-cognate Gly-tRNAAla with 1000-fold higher efficiency than its activity on Gly ...
Santosh Kumar Kuncha, Katta Suma, Komal Ishwar Pawar, Jotin Gogoi, Satya Brata Routh, Sambhavi Pottabathini, Shobha P Kruparani, Rajan Sankaranarayanan   +7 more
doaj   +1 more source

Quaternionic representation of the genetic code [PDF]

, 2015
A heuristic diagram of the evolution of the standard genetic code is presented. It incorporates, in a way that resembles the energy levels of an atom, the physical notion of broken symmetry and it is consistent with original ideas by Crick on the origin ...
Carlevaro, C. Manuel, Irastorza, Ramiro M., Vericat, Fernando   +2 more
core   +3 more sources

NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition

iScience, 2021
Summary: Lipids, such as cholesterol and fatty acids, influence cell signaling, energy storage, and membrane formation. Cholesterol is biosynthesized through the mevalonate pathway, and aberrant metabolism causes metabolic diseases.
Tsuyoshi Waku, Toru Hagiwara, Natsuko Tamura, Yuri Atsumi, Yasuomi Urano, Mikiko Suzuki, Takuya Iwami, Katsuya Sato, Masayuki Yamamoto, Noriko Noguchi, Akira Kobayashi   +10 more
doaj  

Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue

eLife, 2018
Organisms possessing genetic codes with unassigned codons raise the question of how cellular machinery resolves such codons and how this could impact horizontal gene transfer.
Natalie Jing Ma, Colin F Hemez, Karl W Barber, Jesse Rinehart, Farren J Isaacs   +4 more
doaj   +1 more source

A crystal base for the genetic code [PDF]

, 1998
The quantum enveloping algebra U_q(sl(2) \oplus sl(2)) in the limit q \to 0 is proposed as a symmetry algebra for the genetic code. In this approach the triplets of nucleotids or codons in the DNA chain are classified in crystal bases, tensor product of ...
A. Sciarrino, Bashford, Hornos, Kashiwara, L. Frappat, Lewin, P. Sorba, Sachse, Singer   +8 more
core   +3 more sources

Reprogramming the Genetic Code [PDF]

Science, 2011
Incorporating unnatural amino acids into proteins presents challenges in expanding the genetic code.
openaire   +3 more sources

Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022
Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG, Huichun LIU, Wenting XU, Kaiyuan ZHU   +3 more
doaj   +1 more source

Breaking the genetic code – a new revolutionary stage in the development of molecular biology: 1968 Nobel Prize laureates M. W. Nirenberg, H. G. Khorana, R. W. Holley [PDF]

The Ukrainian Biochemical Journal, 2021
This review presents the life stories of M. Nirenberg, H. Khorana, and R. Holley, winners of the 1968 Nobel Prize in Physiology or Medicine, the history of the discoveries made by these scientists, and the methodological approaches used in their works ...
O. P. Matyshevska, V. M. Danilova, S. V. Komisarenko   +2 more
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