Results 81 to 90 of about 431,685 (314)

Gin: Genetic Improvement Research Made Easy [PDF]

open access: yes, 2019
Genetic improvement (GI) is a young field of research on the cusp of transforming software development. GI uses search to improve existing software. Researchers have already shown that GI can improve human-written code, ranging from program repair to ...
David R. White   +23 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Molecular Mechanisms and the Significance of Synonymous Mutations

open access: yesBiomolecules
Synonymous mutations result from the degeneracy of the genetic code. Most amino acids are encoded by two or more codons, and mutations that change a codon to another synonymous codon do not change the amino acid in the gene product.
Peter Oelschlaeger
doaj   +1 more source

Antenna-Diversity-Assisted Genetic-Algorithm-Based Multiuser Detection Schemes for Synchronous CDMA Systems

open access: yes, 2003
A spatial diversity reception assisted multiuser code-division multiple-access detector based on genetic algorithms (GAs) is proposed. Two different GA-based individual-selection strategies are considered. In our first approach, the so-called individuals
Hanzo, L., Yen, K.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Logic in the Light of Cognitive Science

open access: yesStudies in Logic, Grammar and Rhetoric, 2016
Logical theory codifies rules of correct inferences. On the other hand, logical reasoning is typically considered as one of the most fundamental cognitive activities.
Woleński Jan
doaj   +1 more source

`The frozen accident' as an evolutionary adaptation: A rate distortion theory perspective on the dynamics and symmetries of genetic coding mechanisms

open access: yes, 2011
We survey some interpretations and related issues concerning the frozen hypothesis due to F. Crick and how it can be explained in terms of several natural mechanisms involving error correction codes, spin glasses, symmetry breaking and the characteristic
Rodrick Wallace, James F. Glazebrook
core  

Semiotic nature of Genetic code

open access: yes
In some previous works (2018a,b; 2019, 2021a,b, 2022) we presented a new type of mirror symmetry, expressed in the set of protein amino acids; such a symmetry, that it simultaneously represents the semiotic essence of the genetic code.
Miloje, Rakočević
core   +1 more source

Genetic algorithm assisted Joint multiuser symbol detection and fading channel estimation for synchronous CDMA systems

open access: yes, 2001
A novel multiuser code division multiple access (CDMA) receiver based on genetic algorithms is considered, which jointly estimates the transmitted symbols and fading channel coefficients of all the users.
Hanzo, L., Yen, K.
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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