Results 121 to 130 of about 4,241,866 (336)

Property rights, collective action, and plant genetic resources [PDF]

open access: yes
"Many factors affect the conservation of biodiversity, including demographic changes, technological developments, national agricultural policies, and economic, social, and cultural factors.
Dennis, Evan   +3 more
core  

Museum DNA reveals the demographic history of the endangered Seychelles warbler [PDF]

open access: yes, 2014
The importance of evolutionary conservation – how understanding evolutionary forces can help guide conservation decisions – is widely recognized. However, the historical demography of many endangered species is unknown, despite the fact that this can ...
Collar N. J.   +8 more
core   +4 more sources

Purging and accumulation of genetic load in conservation.

open access: yesTrends in Ecology & Evolution, 2023
N. Dussex   +4 more
semanticscholar   +1 more source

Genetic frontiers for conservation: an assessment of synthetic biology and biodiversity conservation: technical assessment

open access: yes, 2019
In recent years synthetic biology has emerged as a suite of techniques and technologies that enable humans to read, interpret, modify, design and manufacture DNA in order to rapidly influence the forms and functions of cells and organisms, with the ...
L. Alphey   +29 more
semanticscholar   +1 more source

An integrated map of genetic variation from 1,092 human genomes

open access: yesNature, 2012
By characterizing the geographic and functional spectrum of human genetic variation, the 1000 Genomes Project aims to build a resource to help to understand the genetic contribution to disease.
Gil A. David M. Richard M. Gonçalo R. David R. Aravind McVean Altshuler (Co-Chair) Durbin (Co-Chair) Abec   +499 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

No evidence for a recent genetic bottleneck in the endangered Sheko cattle breed (African Bos taurus) revealed by microsatellite analysis [PDF]

open access: yes, 2009
Sheko is African taurine cattle, valued for its milk yield, adaptation to humid tsetse infested environment and trypanotolerance. We used 30 microsatellite markers in analyzing 30 DNA samples. We found high genetic diversity and no genetic bottlenecks in
Hailu Dadi   +6 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Genomics and conservation units: The genetic basis of adult migration timing in Pacific salmonids

open access: yesEvolutionary Applications, 2018
It is now routinely possible to generate genomics‐scale datasets for nonmodel species; however, many questions remain about how best to use these data for conservation and management.
R. Waples, S. Lindley
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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