Genetic correlation and causal relationship between sleep and myopia: a mendelian randomization study. [PDF]
Zhu G, Tian R, Zhou D, Qin X.
europepmc +1 more source
Ovulation rate and twinning rate in cattle: heritabilities and genetic correlation.
L.D. Van Vleck+2 more
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Negative genetic correlation between traits of the Drosophila head, and interspecific divergence in head shape [PDF]
Fabian M. Norry+2 more
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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Genetic correlation between genes targeted by lipid-lowering drugs and venous thromboembolism: A drug-target Mendelian randomization study. [PDF]
Li M+7 more
europepmc +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Casual associations between brain structure and sarcopenia: A large-scale genetic correlation and mendelian randomization study. [PDF]
Yang G+6 more
europepmc +1 more source
Correlation of physical and genetic maps of human chromosome 16
G.R. Sutherland
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MIF as an oncogenic driver of low‐heterogeneity melanomas
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran+4 more
wiley +1 more source