Results 51 to 60 of about 1,122,121 (342)
Genetic correlations in grapevine and their effects on selection
Australian Journal of Grape and Wine Research, 2015 Background and Aims The evaluation of genotype-by-environment interaction and the genotypic correlations between important economic traits are two relevant issues of the methodology of grapevine selection that remain insufficiently explored.
Vanda Pedroso +4 more
openaire +2 more sources
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Two Cellular Resource Based Models Linking Growth and Parts Characteristics Aids the Study and Optimization of Synthetic Gene Circuits [PDF]
Engineering Biology 1(1): 30-39 (2017), 2023 A major challenge in synthetic genetic circuit development is the inter-dependency between heterologous gene expressions by circuits and host's growth rate. Increasing heterologous gene expression increases burden to the host, resulting in host growth reduction; which reduces overall heterologous protein abundance.
arxiv
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Genetic parameters in agronomic characters for selection of superior lineages of Ricinus communis L
Ciência Rural, 2019 : Knowledge on the variability and heritability of agronomic characters of interest aid the selection of superior materials. Thus, the objective of this study was to evaluate the genetic parameters of agronomic traits in castor bean plant lineages and to
Laurenice Araujo dos Santos +5 more
doaj +1 more source
Distinguishing correlation from causation using genome-wide association studies [PDF]
O'Connor, Luke J. and Alkes L. Price. "Distinguishing genetic
correlation from causation across 52 diseases and complex traits." Nature
genetics (2018), 2018 Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships.
arxiv
Hot and Cold Nociception Are Genetically Correlated [PDF]
The Journal of Neuroscience, 1999 Recent experiments in our laboratory have revealed a genetic correlation of the sensitivity of inbred mouse strains to different assays of nociception using noxious heat stimuli. An open question is whether the property of the noxious stimulus underlying the genetic correlation is heat specifically or simply a temperature (hot or cold) in the noxious ...
Seetal M. Adhikari, Jeffrey S. Mogil
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Age-age correlation for early selection of rubber tree genotypes in São Paulo State, Brazil
Genetics and Molecular Biology, 2005 In a field trial involving 68 rubber tree (Hevea spp.) clones calculation of genotypic correlation coefficients revealed significant age-age correlation from age 1 to 6 (immature period) for girth A and for age 7 to 12 (mature period) for girth B and for
Paulo de Souza Gonçalves +5 more
doaj +1 more source
Mendelian randomization with fine-mapped genetic data: choosing from large numbers of correlated instrumental variables [PDF]
arXiv, 2017 Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk factor on an outcome. With fine-mapped genetic data, there may be hundreds of genetic variants in a single gene region any of which could be used to assess this causal relationship.
arxiv