Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Relationship between microspatial population genetic structure and habitat heterogeneity in Pomatias elegans (O.F. Müller 1774) (Caenogastropoda, Pomatiasidae) [PDF]
, 2006 In the present study the population genetic structure of the terrestrial snail Pomatias elegans was related to habitat structure on a microspatial scale.
Pfenninger, Markus
core
Geographical Distance and Genetic Differentiation of Some Populations of Tilapia guineensis (Bleeker, 1862) in Nigerian Coastal Waters [PDF]
, 2022 E. A. Ukenye, I. A. Taiwo
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Genetic distance between populations
Theoretical and Applied Genetics, 1982 An excess proportion of homozygous carriers of a gene arises on bulking of reproductively isolated subpopulations. This surplus of homozygotes in the mixture, measured relative to the panmictic proportion, is caused by variation of its frequencies in the respective subpopulations.
openaire +3 more sources
Microsatellite Analysis of Genetic Diversity in Indian Chicken Populations
The Journal of Poultry Science, 2007 Characterization of genetic diversity by employing molecular tools is a prerequisite in developing strategies for conservation and utilization of poultry genetic resources. We assessed genetic variation within and between six Indian chicken populations (
Nasrollah Pirany +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Is there a role for genetics in economic development? [PDF]
Spolaore and Wacziarg (2009) have presented evidence supporting a role of genetic distance to the United States as a barrier to economic development. We extend their empirical work by controlling for the share of Europeans and European descendants in the
Luis Angeles
core
Minimum distance computation of linear codes via genetic algorithms with\n permutation encoding [PDF]
, 2018 José Gómez-Torrecillas +2 more
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Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
Memorias do Instituto Oswaldo Cruz, 2015 The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region.
Natália Spitz +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source