Results 201 to 210 of about 3,031,778 (313)

Genetic drift promotes and recombination hinders speciation on holey fitness landscapes. [PDF]

PLoS Genet
Kalirad A, Burch CL, Azevedo RBR.
europepmc   +1 more source

eLife assessment: Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

Vincent Castric
openalex   +1 more source

Genetic drift and bottleneck do not influence diversity in Toll‐like receptor genes at a small spatial scale in a Himalayan passerine [PDF]

, 2020
Mridula Nandakumar, Farah Ishtiaq
openalex   +1 more source

Genetic drift: the ghost in the genome

Lab animal, 2017
Lina Zeldovich
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A new lysine biosynthetic enzyme from a bacterial endosymbiont shaped by genetic drift and genome reduction. [PDF]

Protein Sci
Gilkes JM, Frampton RA, Board AJ, Hudson AO, Price TG, Morris VK, Crittenden DL, Muscroft-Taylor AC, Sheen CR, Smith GR, Dobson RCJ.   +10 more
europepmc   +1 more source

Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection. [PDF]

Mol Biol Evol, 2021
Armstrong EE, Khan A, Taylor RW, Gouy A, Greenbaum G, Thiéry A, Kang JT, Redondo SA, Prost S, Barsh G, Kaelin C, Phalke S, Chugani A, Gilbert M, Miquelle D, Zachariah A, Borthakur U, Reddy A, Louis E, Ryder OA, Jhala YV, Petrov D, Excoffier L, Hadly E, Ramakrishnan U.   +24 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans. [PDF]

Elife
Bénitière F, Necsulea A, Duret L.
europepmc   +1 more source

Population differences in Chinook salmon (Oncorhynchus tshawytscha) DNA methylation: Genetic drift and environmental factors. [PDF]

Ecol Evol, 2021
Venney CJ, Sutherland BJG, Beacham TD, Heath DD.   +3 more
europepmc   +1 more source