Results 201 to 210 of about 78,579 (231)
Genetic drift versus regional spreading dynamics of COVID-19
, 2020 Pietro RD +3 more
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
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Rett syndrome and genetic drift
Brain and Development, 1999An X chromosome gene is assumed to be responsible for the cause of Rett syndrome (RS). However, new genealogical observations suggest involvement of autosomal recessive gene(s) as well, at least in familial cases. To account for these and other recent observations, the theoretical model presented in 1990 by the authors of this paper is applied to the ...
E M, Bühler, N J, Malik, M, Alkan
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Population Genetics: Consanguinity, Genetic Drift
1997Considerations in the preceding chapters presume random mating, and Hardy-Weinberg proportions are assumed to hold true. However, such assumptions are an abstraction. In modern outbreeding populations mating may approximate randomness for some genetic traits, such as blood groups and enzyme types, but is certainly nonrandom for some traits and some ...
Friedrich Vogel, Arno G. Motulsky
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Crop Science, 2003
Many public sector maize recurrent selection programs have been designed based on additive genetic expectations. Populations have been managed as large metapopulations with the assumption that population size must be very large because inbreeding due to finite size causes a linear reduction in genetic variance; we show that in BS13(S)C0 such ...
Jode W. Edwards, Kendall R. Lamkey
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Many public sector maize recurrent selection programs have been designed based on additive genetic expectations. Populations have been managed as large metapopulations with the assumption that population size must be very large because inbreeding due to finite size causes a linear reduction in genetic variance; we show that in BS13(S)C0 such ...
Jode W. Edwards, Kendall R. Lamkey
openaire +1 more source
Genetic drift in exogamous marriage systems
Theoretical Population Biology, 1975Many mathematical models have been developed to study genetic drift under a variety of assumptions (e.g. Karlin (1968), Crow and Kimura (1970)). Our purpose in this paper is to extend the range of available models by incorporating an additional feature of particular relevance to human populations, to derive certain latent roots for these models, and to
Cannings, C., Skolnick, M. H.
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1980
Random changes are difficult to discuss, in that we cannot (usually) say that some specific change will happen, only that the change is probable or improbable. Statements involving probability are apt to produce discomfort in the reader, a vague sense of entering through a shop door labelled “only abstractions sold here”.
openaire +1 more source
Random changes are difficult to discuss, in that we cannot (usually) say that some specific change will happen, only that the change is probable or improbable. Statements involving probability are apt to produce discomfort in the reader, a vague sense of entering through a shop door labelled “only abstractions sold here”.
openaire +1 more source
2016
Genetic drift is a random process that can lead to the fixation of alleles, but at the cost of losing alleles, especially those with low frequencies, and to increased homozygosity in the population. This process is described for an idealised population and its effect illustrated on different population sizes.
openaire +1 more source
Genetic drift is a random process that can lead to the fixation of alleles, but at the cost of losing alleles, especially those with low frequencies, and to increased homozygosity in the population. This process is described for an idealised population and its effect illustrated on different population sizes.
openaire +1 more source