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Genetic engineering and the eye. [PDF]

open access: yesEye (Lond)
Abstract The transformative potential of genetic engineering in ophthalmology is remarkable, promising new treatments for a wide range of blinding eye diseases. The eye is an attractive target organ for genetic engineering approaches, in part due to its relatively immune-privileged status, its accessibility, and the ease of monitoring of ...
Murphy R, Martin KR.
europepmc   +3 more sources

Genetic Engineering of Humanized Telomere Mice [PDF]

open access: yesBio-Protocol
Telomere shortening is a hallmark of human aging, and telomerase regulation plays a critical role in cellular proliferation and replicative senescence. In human cells, telomere length imposes a limit on proliferative potential, a phenomenon known as the ...
Fan Zhang   +4 more
doaj   +2 more sources

Genetic Engineering for Cereal Crop Yield Improvement and Disease Resistant Breeding [PDF]

open access: yesThe Scientific World Journal
Genetic engineering has revolutionized the field of agriculture, providing innovative solutions to enhance crop productivity and resilience against diseases.
Asaye Demelash Limenie, Mastewal Alehegn
doaj   +2 more sources

Nanodelivery of nucleic acids for plant genetic engineering [PDF]

open access: yesDiscover Nano
Genetic engineering in plants serves as a crucial method for enhancing crop quality, yield, and climate resilience through the manipulation of genetic circuits.
Shufeng Liu   +6 more
doaj   +2 more sources

Genetic engineering for haemophilia A

open access: greenExpert Opinion on Biological Therapy, 2006
At first sight, haemophilia A would appear to be an ideal candidate for treatment by gene therapy. There is a single gene defect; cells in different parts of the body, but especially the liver, produce Factor VIII, and only 5% of normal levels of Factor VIII are necessary to prevent the serious symptoms of bleeding.
Shu Uin Gan, Oi Lian Kon, Roy Calne
openalex   +4 more sources

RNA Interference-Based Genetic Engineering Maize Resistant to Apolygus lucorum Does Not Manifest Unpredictable Unintended Effects Relative to Conventional Breeding: Short Interfering RNA, Transcriptome, and Metabolome Analysis

open access: yesFrontiers in Plant Science, 2022
The use of omics techniques to analyze the differences between genetic engineering organisms and their parents can identify unintended effects and explore whether such unintended effects will have negative consequences.
Chunmeng Huang   +10 more
doaj   +1 more source

Genetic Engineering Technologies for Improving Crop Yield and Quality

open access: yesAgronomy, 2022
Genetic engineering refers to the specific molecular biological modification of DNA sequences. With the rapid development of genetic engineering methods, especially the breakthroughs in guiding endonuclease technology, gene remodeling of crops has become
Runle Ye, Xi Yang, Yuchun Rao
doaj   +1 more source

Genetic engineering for the environment: Ethical implications of the biotechnology revolution [PDF]

open access: yes, 1995
This is a PDF version of an article published in Heythrop Journal© 1995. The definitive version is available at www.blackwell-synergy.com.This article discusses the environmental consequences of genetic engineering for agricultural purposes within a ...
Deane-Drummond, Celia
core   +1 more source

Developing capabilities in the seed industry: which direction to follow? [PDF]

open access: yes, 2014
Since the 1990s, many developing country policy makers have assumed that plant genetic engineering represents the only technological frontier in seed innovation; that it has been the leading technology for improving seeds and agricultural performance in ...
Marin, Anabel   +2 more
core   +2 more sources

Combinatorial approaches for inverse metabolic engineering applications

open access: yesComputational and Structural Biotechnology Journal, 2012
Traditional metabolic engineering analyzes biosynthetic and physiological pathways, identifies bottlenecks, and makes targeted genetic modifications with the ultimate goal of increasing the production of high-value products in living cells.
Georgios Skretas, Fragiskos N Kolisis
doaj   +3 more sources

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