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Genetic Engineering of Humanized Telomere Mice [PDF]
Bio-ProtocolTelomere shortening is a hallmark of human aging, and telomerase regulation plays a critical role in cellular proliferation and replicative senescence. In human cells, telomere length imposes a limit on proliferative potential, a phenomenon known as the ...
Fan Zhang +4 more
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Genetic engineering and the eye. [PDF]
Eye (Lond)Abstract The transformative potential of genetic engineering in ophthalmology is remarkable, promising new treatments for a wide range of blinding eye diseases. The eye is an attractive target organ for genetic engineering approaches, in part due to its relatively immune-privileged status, its accessibility, and the ease of monitoring of ...
Murphy R, Martin KR.
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Genetic Engineering for Cereal Crop Yield Improvement and Disease Resistant Breeding [PDF]
The Scientific World JournalGenetic engineering has revolutionized the field of agriculture, providing innovative solutions to enhance crop productivity and resilience against diseases.
Asaye Demelash Limenie, Mastewal Alehegn
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Nanodelivery of nucleic acids for plant genetic engineering [PDF]
Discover NanoGenetic engineering in plants serves as a crucial method for enhancing crop quality, yield, and climate resilience through the manipulation of genetic circuits.
Shufeng Liu +6 more
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Genetic engineering in organoids [PDF]
Journal of Molecular Medicine, 2021 AbstractThree-dimensional organoids have been widely used for developmental and disease modeling. Organoids are derived from both adult and pluripotent stem cells. Various types are available for mimicking almost all major organs and tissues in the mouse and human.
Isaree Teriyapirom +2 more
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Frontiers in Plant Science, 2022 The use of omics techniques to analyze the differences between genetic engineering organisms and their parents can identify unintended effects and explore whether such unintended effects will have negative consequences.
Chunmeng Huang +10 more
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Genetic Engineering Technologies for Improving Crop Yield and Quality
Agronomy, 2022 Genetic engineering refers to the specific molecular biological modification of DNA sequences. With the rapid development of genetic engineering methods, especially the breakthroughs in guiding endonuclease technology, gene remodeling of crops has become
Runle Ye, Xi Yang, Yuchun Rao
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The arrival of genetic engineering [PDF]
IEEE Engineering in Medicine and Biology Magazine, 2009 The purpose of this article is to review the different strategies for the delivery of plasmid DNA (pDNA)-based gene therapy. Plasmids are extrachromosomal DNA capable of being transmitted from cell to cell. They are supercoiled, circular covalently closed (ccc) strands of DNA capable of replication independently of host DNA and ranging from 5 to 400 ...
Arulmuthu, E. +2 more
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Principles of Genetic Engineering [PDF]
Genes, 2020 Genetic engineering is the use of molecular biology technology to modify DNA sequence(s) in genomes, using a variety of approaches. For example, homologous recombination can be used to target specific sequences in mouse embryonic stem (ES) cell genomes or other cultured cells, but it is cumbersome, poorly efficient, and relies on drug positive/negative
Thomas M. Lanigan +2 more
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Combinatorial approaches for inverse metabolic engineering applications
Computational and Structural Biotechnology Journal, 2012 Traditional metabolic engineering analyzes biosynthetic and physiological pathways, identifies bottlenecks, and makes targeted genetic modifications with the ultimate goal of increasing the production of high-value products in living cells.
Georgios Skretas, Fragiskos N Kolisis
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