Results 111 to 120 of about 2,745,050 (303)

Genetic Epidemiology [electronic resource] /

Arising from firm foundations laid by mathematical population genetics, clinical genetics, and statistical epidemiology, genetic epidemiology attempts to identify the many components of risk attributable to genes, environments, and interactions, and the ...
SpringerLink (Online service), Teare, M. Dawn.editor.edthttp://id.loc.gov/vocabulary/relators/edt   +1 more
core   +1 more source

Genetic Epidemiology in Germany

, 2005
Summary Objectives: Genetic epidemiology investigates the role of genetic factors and their interaction with environmental factors (in a broad meaning) for the occurrence of diseases in human populations.
H.-E. Wichmann
core   +1 more source

Genetic Epidemiology of Breast Cancer in Latin America [PDF]

, 2019
The last 10 years witnessed an acceleration of our understanding of what genetic factors underpin the risk of breast cancer. Rare high- and moderate-penetrance variants such as those in the BRCA genes account for a small proportion of the familial risk ...
Zavala, Valentina A, Silvia J. Serrano-Gomez, Fejerman, Laura, Valentina A. Zavala, Laura Fejerman, Dutil, Julie, Serrano-Gomez, Silvia J, Julie Dutil   +7 more
core   +1 more source

Nonparametric Methods and Evolutionary Algorithms in Genetic Epidemiology

, 2018
Paper overviews variable selection problem in high dimensionality, particularly focused on genetic psychiatry and genetic epidemiology in general. Genetic and quantum evolutionary algorithms, tree-based classification/regression models, random forest ...
Colleen Molloy Farrelly
core   +2 more sources

Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue

BMC Genomics, 2018
Background Intermittent fasting and time-restricted diets are associated with lower risk biomarkers for cardio-metabolic disease. The shared mechanisms underpinning the similar physiological response to these events is not established, but circadian ...
Alexessander Couto Alves, Craig A. Glastonbury, Julia S. El-Sayed Moustafa, Kerrin S. Small   +3 more
doaj   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population

, 2019
Hereditary hearing impairment (HHI) is a common but heterogeneous clinical entity caused by mutations in a plethora of deafness genes. Research over the past few decades has shown that the genetic epidemiology of HHI varies significantly across ...
Yin-Hung Lin, Chee-Yee Lee, Yen-Fu Cheng, Yi-Hsin Lin, Tien-Chen Liu, Cheng-Yu Tsai, Pei-Hsuan Lin, Jargalkhuu Erdenechuluun, Chen-Chi Wu, Che-Ming Wu, Pey-Yu Chen, Chuan-Jen Hsu, Pei-Lung Chen   +12 more
core   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Temporal Divergence of True and False Alarms in Pediatric Nocturnal Seizure Monitoring

Annals of Clinical and Translational Neurology, EarlyView.
The early‐morning surge in false seizure alarms supports exploring time‐ or state‐dependent detection thresholds to reduce false detections. ABSTRACT Seizure detection devices can improve the safety of children with epilepsy, yet high false alarms limit their clinical applicability.
Mohammad Shahbakhti, Anemoon T. Bosch, Job van der Palen, Franciscus S. Leijten, Johannes P. van Dijk, Richard H. C. Lazeron, Roland D. Thijs   +6 more
wiley   +1 more source