Results 121 to 130 of about 2,745,050 (303)

Ethics and Epidemiology

, 2009
Contributors -- Pt. I. Foundations -- 1. Historical foundations / Steven S. Coughlin -- 2. Moral foundations / Tom L. Beauchamp -- 3. Toward a philosophy of epidemiology / Douglas L. Weed -- Pt. II. Informed consent, privacy, and confidentiality --

core  

Post-genome respiratory epidemiology: A multidisciplinary challenge.

, 2004
The introduction of genetic approaches in respiratory epidemiology is novel for most epidemiologists, and the post-genome phase poses new challenges. After describing specific questions pertinent to the field of asthma and chronic obstructive pulmonary ...
Post Genome Respiratory Epidemiology Group (Wjst, M.), Kauffmann, F.   +1 more
core   +1 more source

Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches

BMC Medicine
Background Maternal stress during pregnancy may impact offspring development via changes in the intrauterine environment. However, genetic and environmental factors shared between mothers and children might skew our understanding of this pathway.
Ingunn Olea Lund, Laurie J. Hannigan, Helga Ask, Adrian D. Askelund, Laura Hegemann, Elizabeth C. Corfield, Robyn E. Wootton, Yasmin I. Ahmadzadeh, George Davey Smith, Tom A. McAdams, Eivind Ystrom, Alexandra Havdahl   +11 more
doaj   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Data supporting Harris et al. "Molecular genetic contributions to self-rated health" (International Journal of Epidemiology)

, 2019
Data supporting paper Harris et al. "Molecular genetic contributions to self-rated health" (International Journal of Epidemiology)Harris, SE; Hagenaars, SP; Davies, G; Hill, DW; Liewald, DCM; Ritchie, SJ; Marioni, RE; Sudlow, CLM; Wardlaw, JM; Gale, C ...
Edinburgh Neuroscience, School of Regeneration and Repair, School of Population Health Sciences, Liewald, David, Deary, Ian, Marioni, Riccardo, Harris, Sarah, Centre for Medical Informatics, Davies, Gail, Ritchie, Stuart, Centre for Genomic and Experimental Medicine, School of Philosophy, Psychology and Language Sciences, Sudlow, Catherine; id_orcid, Hill, David, Usher Institute, Gale, Catharine, Edinburgh Imaging, Centre for Clinical Brain Sciences, Wardlaw, Joanna, Hagenaars, Saskia   +19 more
core   +1 more source

Incident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population‐Based Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the incidence of diabetes mellitus and its associations with hospitalisation and mortality in adults with multiple sclerosis (MS) and matched controls. Methods Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 ...
Yolanda Lau, Sedigheh Zabihi, Morghan Hartmann, Georgina Mathlin, Sube Banerjee, Ebaa Marouf, Clare Hadley, Claudia Cooper, Ruth Dobson   +8 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu, Peng Guo, Rui Pan, Zhenghao Wang, Jingchao Zhou, Pengcheng Zhang, Xingzhe Zhang, Qinghua Zhang, Haibin Ma, Zhanfeng Niu   +9 more
wiley   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Correction to: Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome

BMC Microbiology, 2022
Caroline Ivanne Le Roy, Alexander Kurilshikov, Emily R. Leeming, Alessia Visconti, Ruth C. E. Bowyer, Cristina Menni, Mario Fachi, Hana Koutnikova, Patrick Veiga, Alexandra Zhernakova, Muriel Derrien, Tim D. Spector   +11 more
doaj   +1 more source