Results 171 to 180 of about 731,889 (291)

Editorial: Women in applied genetic epidemiology. [PDF]

open access: yesFront Genet
Guo Q, Allen-Brady K, Olszewska M.
europepmc   +1 more source

Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts. [PDF]

open access: yesChest, 2023
Choi B   +29 more
europepmc   +1 more source

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo   +13 more
wiley   +1 more source

Genetic Epidemiology and Resistance Investigations of Clinical Yeasts in Alexandria, Egypt. [PDF]

open access: yesPathogens
Spruijtenburg B   +9 more
europepmc   +1 more source

Genetic epidemiology of autoinflammatory disease variants in Indian population from 1029 whole genomes. [PDF]

open access: yesJ Genet Eng Biotechnol, 2021
Jain A   +50 more
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma   +17 more
wiley   +1 more source

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