Results 11 to 20 of about 735,632 (337)

Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly – comparative results from the KORA and AugUR study

open access: yesBMC Genomic Data, 2023
Background Polygenic scores (PGSs) combining genetic variants found to be associated with creatinine-based estimated glomerular filtration rate (eGFRcrea) have been applied in various study populations with different age ranges.
Janina M. Herold   +13 more
doaj   +1 more source

Ecogeographic genetic epidemiology [PDF]

open access: yesGenetic Epidemiology, 2008
AbstractComplex diseases such as cancer and heart disease result from interactions between an individual's genetics and environment, i.e. their human ecology. Rates of complex diseases have consistently demonstrated geographic patterns of incidence, or spatial “clusters” of increased incidence relative to the general population.
Chantel D, Sloan   +6 more
openaire   +2 more sources

Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome

open access: yesBMC Microbiology, 2022
Background Yoghurt contains live bacteria that could contribute via modulation of the gut microbiota to its reported beneficial effects such as reduced body weight gain and lower incidence of type 2 diabetes.
Caroline Ivanne Le Roy   +11 more
doaj   +1 more source

Genetic epidemiology [PDF]

open access: yesBritish Medical Bulletin, 1996
Studies of families, twins, and adoptees have helped to quantify the genetic contributions to and overlaps between depression, anxiety, phobias and alcoholism, and to refine the boundaries of the schizophrenia spectrum. Analyses of covariance structures in twin data have confirmed genetic susceptibility and recent life stresses as the major ...
openaire   +3 more sources

Monitoring genetic population biomarkers for wastewater-based epidemiology [PDF]

open access: yes, 2017
We report a rapid “sample-to-answer” platform that can be used for the quantitative monitoring of genetic biomarkers within communities through the analysis of wastewater. The assay is based on the loop-mediated isothermal amplification (LAMP) of nucleic
Cooper, Jonathan M.   +4 more
core   +3 more sources

Genetic epidemiology: Systemic sclerosis [PDF]

open access: yesArthritis Research & Therapy, 2002
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised phenotypically by fibrosis and ischaemic atrophy. Its aetiology is most likely multifactorial. A genetic predisposition to the condition is suggested by reports of familial SSc (a positive family history is the strongest risk factor yet identified), by animal models, and ...
Herrick, Ariane L., Worthington, Jane
openaire   +3 more sources

Combined association and linkage analysis applied to the APOE locus. [PDF]

open access: yes, 2004
Combined association and linkage analysis is a powerful tool for pinpointing functional quantitative traits (QTLs) responsible for regions of significant linkage identified in genome-wide scans.
Abecasis   +31 more
core   +1 more source

An in-depth analysis of the mitochondrial phylogenetic landscape of Cambodia

open access: yesScientific Reports, 2021
Cambodia harbours a variety of human aboriginal populations that have scarcely been studied in terms of genetic diversity of entire mitochondrial genomes.
Anita Kloss-Brandstätter   +9 more
doaj   +1 more source

The justification of studies in genetic epidemiology: political scaling in China Medical City [PDF]

open access: yes, 2018
Genetic epidemiology examines the role of genetic factors in determining health and disease in families and in populations to help addressing health problems in a responsible manner.
Sleeboom-Faulkner, Margaret
core   +1 more source

Changes in healthcare seeking and lifestyle in old aged individuals during COVID-19 lockdown in Germany: the population-based AugUR study

open access: yesBMC Geriatrics, 2022
Background Containment measures in the COVID-19 pandemic protected individuals at high risk, particularly individuals at old age, but little is known about how these measures affected health-related behavior of old aged individuals.
Caroline Brandl   +7 more
doaj   +1 more source

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