Results 71 to 80 of about 1,500,618 (293)
DNA replication fork speed acts as a pacer in cortical neurogenesis
Nature CommunicationsDNA replication fork speed, which controls the rate of genome duplication, has emerged as a key regulator of cellular plasticity. However, its role in neurogenesis remains unexplored.
Jianhong Wang +6 more
doaj +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
BMC GenomicsCyprinids, the largest and most economically significant family of teleosts, comprise over 600 polyploid species, whose genomic complexity presents challenges in deciphering the genetic basis of phenotypic diversity.
Yanhui Yin +7 more
doaj +1 more source
BMC Evolutionary Biology, 2018 Background Past climatological events and contemporary geophysical barriers shape the distribution, population genetic structure, and evolutionary history of many organisms. The Himalayan region, frequently referred to as the third pole of the Earth, has
Laxman Khanal +3 more
doaj +1 more source
TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
Nature Communications, 2020 Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. Here the authors found that TDP-43, a RNA-binding protein, is required for milk lipid secretion by post-transcriptional regulation of Btn1a1 and
Limin Zhao +16 more
doaj +1 more source
Genetic algorithm dynamics on a rugged landscape
, 1999 The genetic algorithm is an optimization procedure motivated by biological evolution and is successfully applied to optimization problems in different areas.
A. E. Nix +19 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Supporting Survivor‐Centered Care Through Digital Health Integration
Pediatric Blood &Cancer, EarlyView.ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak +15 more
wiley +1 more source
Decline in blood hemoglobin concentrations is associated with familial longevity [PDF]
Archives of Biological Sciences, 2016 Hemoglobin(HGB)in the blood carries oxygen from the lungs to other organs to produce energy. Calorie restriction has been shown to slow aging and extend lifespan.
He Yong-Han +12 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source