Results 71 to 80 of about 1,488,947 (292)

Riverine barrier effects on population genetic structure of the Hanuman langur (Semnopithecus entellus) in the Nepal Himalaya

BMC Evolutionary Biology, 2018
Background Past climatological events and contemporary geophysical barriers shape the distribution, population genetic structure, and evolutionary history of many organisms. The Himalayan region, frequently referred to as the third pole of the Earth, has
Laxman Khanal, Mukesh Kumar Chalise, Tao Wan, Xuelong Jiang   +3 more
doaj   +1 more source

Genetic algorithm dynamics on a rugged landscape

, 1999
The genetic algorithm is an optimization procedure motivated by biological evolution and is successfully applied to optimization problems in different areas.
A. E. Nix, A. M. Turing, A. Prügel-Bennett, A. Prügel-Bennett, B. Derrida, B. Manderick, C. R. Darwin, E. Aarts, G. J. Friedman, G. J. Koehler, J. H. Holland, J. von Neumann, M. D. Vose, M. Rattray, N. Wiener, P. Sutton, S. Bornholdt, S. Kauffman, S. Kauffman, Stefan Bornholdt   +19 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Decline in blood hemoglobin concentrations is associated with familial longevity [PDF]

Archives of Biological Sciences, 2016
Hemoglobin(HGB)in the blood carries oxygen from the lungs to other organs to produce energy. Calorie restriction has been shown to slow aging and extend lifespan.
He Yong-Han, Pu Shao-Yan, Li Wen, Chen Xiao-Qiong, Xiao Fu-Hui, Yan Dong-Jing, Liu Yao-Wen, Lin Rong, Liao Xiao-Ping, Yang Xing-Li, Ge Ming-Xia, Cai Wang-Wei, Kong Qing-Peng   +12 more
doaj   +1 more source

Evolution of organoid genetics

European Journal of Cell Biology
Organoids have revolutionized in vitro research by offering three-dimensional, multicellular systems that recapitulate the structure, function, and genetics of human tissues. Initially developed from both pluripotent stem cells (PSCs) and adult stem cells (AdSCs), organoids have expanded to model nearly every major human organ, significantly advancing ...
Thomas M. Klompstra, Ki-Jun Yoon, Bon-Kyoung Koo   +2 more
openaire   +3 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Evolution of the most recent common ancestor of a population with no selection

, 2006
We consider the evolution of a population of fixed size with no selection. The number of generations $G$ to reach the first common ancestor evolves in time.
Bernard Derrida, Damien Simon, Derrida B, Drummond A J, Durrett R, Fisher R A, Fu Y-X, Hein J, Kaplan N L, Kimura M, Kimura M, Schweinsberg J, Serva M, Tajima F, Tavaré S, Wakeley J, Wiuf C, Wright S   +17 more
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Whole-genome DNA methylomes of tree shrew brains reveal conserved and divergent roles of DNA methylation on sex chromosome regulation

BMC Biology
Background The tree shrew (Tupaia belangeri) is a promising emerging model organism in biomedical studies, notably due to their evolutionary proximity to primates.
Dongmin R. Son, Yifan Kong, Yulian Tan, Ting Hu, Lei Shi, Soojin V. Yi   +5 more
doaj   +1 more source