Results 141 to 150 of about 6,543,071 (370)
Estimation of realized rates of genetic gain and indicators for breeding program assessment
bioRxiv, 2018 Routine estimation of the rate of genetic gain (ΔGt) realized by a breeding program has been proposed as a means to monitor its effectiveness. Several methods of realized ΔGt estimation have been utilized in other studies, but none have been objectively ...
Jessica Rutkoski
semanticscholar +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Journal of Dairy Science, 2019 Both small dairy cattle populations and dairy cattle populations with a low level of linkage disequilibrium (LD) suffer from low reliability of genomic prediction.
J. Thomasen, Huiming Liu, A. Sørensen
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Analisa Genetic Gain Anakan Ikan Nila Pandu (Oreochromis Niloticus) F5 Hasil Pembesaran I [PDF]
, 2012 Budidaya ikan nila (O. niloticus) di Indonesia berkembang cukup pesat. Hal tersebut didukung oleh peluang pasar cukup besar baik di pasar lokal maupun ekspor. Teknik budidaya ikan nila dinilai cukup mudah.
Ayu, N. D. (Nurin), Hastuti, S. (Sri)
core
Theoretical and Applied Genetics, 2017 Key messageOptimal cross selection increases long-term genetic gain of two-part programs with rapid recurrent genomic selection. It achieves this by optimising efficiency of converting genetic diversity into genetic gain through reducing the loss of ...
G. Gorjanc, R. Gaynor, J. Hickey
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Effective population size and genetic gain expected in a population of Coffea canephora
Crop Breeding and Applied Biotechnology, 2019 This work aimed to study the effective population size and genetic gain in a population of robusta coffee (Coffea canephora Pierre) and verify the possibility of using recurrent selection.
J. C. Mistro +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source