Results 141 to 150 of about 1,195,293 (349)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Simulations of rate of genetic gain in dry bean breeding programs. [PDF]

Theor Appl Genet, 2023
Lin J, Arief V, Jahufer Z, Osorno J, McClean P, Jarquin D, Hoyos-Villegas V.   +6 more
europepmc   +1 more source

Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q [PDF]

, 1997
Kerstin Heselmeyer, Merryn Macville, Evelin Schröck, Harald Blegen, Ann Hellström, Keerti V. Shah, Gert Auer, Thomas Ried   +7 more
openalex   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Economic benefits of herd genotyping and using sexed semen for pure and beef-on-dairy breeding in dairy herds

Journal of Dairy Science
: The cost benefits of herd genotyping and the benefits of using sexed semen have been affected by recent improvements in sexing technologies, incorporation of direct health traits in the German total merit index for Holstein cattle, deteriorating prices
Robin Wellmann, Anke Rolfes, Stefan Rensing, Jörn Bennewitz   +3 more
doaj  

Genetic gain and inbreeding from simulation of different genomic mating schemes for pig improvement. [PDF]

J Anim Sci Biotechnol, 2023
Zhao F, Zhang P, Wang X, Akdemir D, Garrick D, He J, Wang L.   +6 more
europepmc   +1 more source

Internationalising to create Firm Specific Advantages: Leapfrogging strategies of U.S. Pharmaceutical firms in the 1930s and 1940s & Indian Pharmaceutical firms in the 1990s and 2000s [PDF]

Internationalisation is a useful strategy to gain firm specific advantages during periods of technological discontinuity. The pharmaceutical industry offers us two such episodes as examples: when the antibiotics revolution was beginning and when the ...
Athreye, Suma, Godley, Andrew
core  

Are genetic determinants of weight gain modified by leisure-time physical activity? A prospective study of Finnish twins [PDF]

, 1997
Berit L. Heitmann, Jaakko Kaprio, J. R. Harris, A Rissanen, Maarit Korkeila, M. Koskenvuo   +5 more
openalex   +1 more source

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

FEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston, Jérôme Feuillard, Aurélie Ancelin, Joséphine Lai‐Kee‐Him, Konstantin Brodolin, Christian Chalut, Pontus Gourdon, Mickaël Blaise   +7 more
wiley   +1 more source

Genetic variability of fenugreek (Trigonella foenum-graecum L.) accessions from agroecological and morphoagronomic traits, Ethiopia

Beverage Plant Research
To develop crops through selection or hybridization, evidence of accession variability is required. The purpose of this study was to collect information on the variability of Trigonella foenum-graecum L.
Rameto Roba, Wassu Mohammed
doaj   +1 more source