Results 21 to 30 of about 53,382 (296)

Exploration of the Genetic Architecture of Idiopathic Generalized Epilepsies [PDF]

Epilepsia, 2006
Summary:  Purpose: Idiopathic generalized epilepsy (IGE) accounts for ∼20% of all epilepsies and affects about 0.2% of the general population. The etiology of IGE is genetically determined, but the complex pattern of inheritance suggests an involvement of a large number of susceptibility genes.
Hempelmann A., Taylor K. P., Heils A., Lorenz S., Prud'Homme J. -F., Nabbout R., Dulac O., Rudolf G., Zara F., Bianchi A., Robinson R., Mark Gardiner R., Covanis A., Lindhout D., Stephani U., Elger C. E., Weber Y. G., Lerche H., Nurnberg P., Kron K. L., Scheffer I. E., Mulley J. C., Berkovic S. F., Sander T.   +23 more
openaire   +4 more sources

Febrile Seizures in Idiopathic/Genetic Generalized and Self-Limited Focal Epilepsies

Archives of Epilepsy, 2021
Objectives:Febrile seizure (FS) is the most common form of childhood seizures. Furthermore, idiopathic/generalized and focal/self-limited epilepsies present at the similar age-range. They usually have a favorable outcome.
Feray BÖLÜKBAŞI TÜMAY, Mecbure NALBANTOĞLU, Rahşan İNAN, Figen YAVLAL, Veysi DEMİRBİLEK   +4 more
doaj   +1 more source

Investigation of the Genetic Etiology in Idiopathic Generalized Epileptic Disorders by Targeted Next-generation Sequencing Technique

Balkan Medical Journal, 2023
Background: Idiopathic generalized epilepsy is the most common group of epilepsy disorders in children and adolescents. Various types of genetic abnormality were identified among the hereditary factors that explain epilepsy.
Engin Atlı, Hakan Gürkan, Babürhan Güldiken, Damla Eker, Sinem Yalçıntepe, Selma Demir, Emine İkbal Atlı   +6 more
doaj   +1 more source

Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]

, 2017
The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji, Bathen-Noethen, Andrea, Bhatti, Sofie, Boettcher, Irene C, Cortez, Miguel A, Dietschi, Elisabeth, Fischer, Andrea, Flegel, Thomas, Hytönen, Marjo K, Hülsmeyer, Velia, James, Fiona, Kluger, Gerhard, Kornberg, Marion, Koskinen, Lotta LE, Leeb, Tosso, Lohi, Hannes, Matiasek, Kaspar, Rentmeister, Kai, Sarviaho, Riika, Tipold, Andrea, Tästensen, Carina, Wielaender, Franziska   +21 more
core   +1 more source

Role of genetics in the etiopathogenesis of genetic generalized epilepsy: A review of current literature

Sahel Medical Journal, 2016
Until recently, genetic generalized epilepsy (GGE) was believed to be of presumed genetic etiology with no identifiable genetic mutation or demonstrable epigenetic abnormality. A wide range of epileptic disorders has clue for an inherited susceptibility.
S A Balarabe, M M Watila
doaj   +1 more source

Effects of patient and seizure-related factors on drug load in seizure-free patients with idiopathic generalized epilepsy

Neurological Sciences and Neurophysiology, 2021
Introduction: Idiopathic generalized epilepsies (IGEs) include four different epilepsy syndromes and IGE have mostly a good response to antiepileptic drugs (AEDs). The most common IGE subgroup is juvenile myoclonic epilepsy (JME).
Fulya Eren, Günay Gül
doaj   +1 more source

"Electro-clinical Syndromes" with onset in Paediatric Age. the highlights of the clinical-EEG, genetic and therapeutic advances [PDF]

, 2011
The genetic causes underlying epilepsy remain largely unknown, and the impact of available genetic data on the nosology of epilepsy is still limited.
PARISI, Pasquale, Alberto Verrotti, PAOLINO, MARIA CHIARA, CASTALDO, Rosa, Filomena Ianniello, FERRETTI, ALESSANDRO, Francesco Chiarelli, VILLA, MARIA PIA   +7 more
core   +1 more source

Genetic Causes of Generalized Epilepsies [PDF]

Seminars in Neurology, 2015
Generalized epilepsies, particularly the idiopathic or genetic generalized epilepsies (GGEs), represent some of the most common epilepsies. Clinical genetic data including family studies and twin studies provide compelling evidence for a prominent genetic impact.
openaire   +2 more sources

White Matter Abnormalities in Patients with Treatment-Resistant Genetic Generalized Epilepsies. [PDF]

, 2016
BACKGROUND Genetic generalized epilepsies (GGEs) are associated with microstructural brain abnormalities that can be evaluated with diffusion tensor imaging (DTI). Available studies on GGEs have conflicting results.
Allendorfer, Jane B, Deutsch, Georg, Gaston, Tyler E, Knowlton, Robert C, Lee, Seongtaek, Pati, Sandipan, Szaflarski, Jerzy P, Ver Hoef, Lawrence W   +7 more
core   +2 more sources

Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility

Saudi Pharmaceutical Journal, 2019
Background: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and ...
Laith N. AL-Eitan, Islam M. Al-Dalalah, Hanan A. Aljamal   +2 more
doaj   +1 more source