Results 51 to 60 of about 53,278 (329)
Audiogenic reflex seizures in cats [PDF]
, 2015 This study aims at characterizing feline audiogenic reflex seizures (FARS). An online questionnaire was developed to capture information from owners with cats suffering FARS.
Bessant, C +4 more
core +2 more sources
Unravelling the brain networks driving spike-wave discharges in genetic generalized epilepsy-common patterns and individual differences. [PDF]
Epilepsia Open, 2018 Klamer S +9 more
europepmc +3 more sources
Saudi Pharmaceutical Journal, 2019 Background: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and ...
Laith N. AL-Eitan +2 more
doaj +1 more source
Epilepsy & Behavior Reports, 2021 We report a patient with a 6q22.1 deletion, who presented with a rare syndrome of generalized epilepsy, myoclonic tremor, and intellectual disability. There was no clinical progression after follow-up for more than 10 years.
Kazuhiro Haginoya +11 more
doaj +1 more source
Genetic epilepsy with febrile seizures plus – an overview [PDF]
Romanian Journal of Neurology, 2021 Genetic epilepsy with febrile seizures plus (GEFS+) is characterized by a group of genetic epilepsies associated predominately with an autosomal dominant pattern, but also with de novo and autosomal-recessive inheritance, these last two found in a small ...
Madalina Radu +3 more
doaj +1 more source
Generalized epilepsies: current conceptions and therapeutic approaches
Неврология, нейропсихиатрия, психосоматика, 2012 The concepts of generalized epilepsy have recently undergone considerable changes: the features of focality in generalized epilepsies and the typical features of idiopathic generalized epilepsies in focal epilepsies have been revealed.
L R Zenkov
doaj +1 more source
Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]
, 2018 The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core +1 more source
The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]
, 2020 Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco +4 more
core +1 more source
Unmasking of myoclonus by lacosamide in generalized epilepsy
Epilepsy and Behavior Case Reports, 2017 Lacosamide is a new-generation antiseizure medication that is approved for use as an adjunctive treatment and monotherapy in focal epilepsy. Its use in generalized epilepsy, however, has not been adequately evaluated in controlled trials.
Daniel Birnbaum, Mohamad Koubeissi
doaj +1 more source
Genetics of Idiopathic Generalized Epilepsies [PDF]
Epilepsia, 2005 Summary: The idiopathic generalized epilepsies (IGEs) are considered to be primarily genetic in origin. They encompass a number of rare mendelian or monogenic epilepsies and more common forms which are familial but manifest as complex, non‐mendelian traits. Recent advances have demonstrated that many monogenic IGEs are ion channelopathies.
openaire +2 more sources