Results 21 to 30 of about 483,969 (264)

Recurrent Glioma With Lineage Conversion From Oligodendroglioma to Astrocytoma in Two Cases

Frontiers in Oncology, 2019
Following the introduction of the molecular classification of gliomas by the WHO in 2016, molecularly-proven lineage conversion during glioma recurrence has never been reported. The reported two cases were initially diagnosed as oligodendroglioma with 1p/
Jo-Heon Kim, Woo-Youl Jang, Tae-Young Jung, Shin Jung, Kyung-Keun Kim, Hyung-Seok Kim, Eun-Hee Kim, Min-Cheol Lee, Kyung-Sub Moon, Kyung-Hwa Lee   +9 more
doaj   +1 more source

Leukemic Stem Cells: From Leukemic Niche Biology to Treatment Opportunities

Frontiers in Immunology, 2021
Acute myeloid leukemia (AML) is one of the most common types of leukemia in adults. While complete remission can be obtained with intensive chemotherapy in young and fit patients, relapse is frequent and prognosis remains poor. Leukemic cells are thought
Tony Marchand, Tony Marchand, Tony Marchand, Sandra Pinho   +3 more
doaj   +1 more source

Genetic Heterogeneity in Familial Hyperinsulinism [PDF]

Human Molecular Genetics, 1998
Familial hyperinsulinism (HI) is a disorder characterized by dysregulation of insulin secretion and profound hypoglycemia. Mutations in both the Kir6.2 and sulfonylurea receptor (SUR1) genes have been associated with the autosomal recessive form of this disorder.
A, Nestorowicz, B, Glaser, B A, Wilson, S L, Shyng, C G, Nichols, C A, Stanley, P S, Thornton, M A, Permutt   +7 more
openaire   +2 more sources

Genetic Evaluation of Patients with Clinically Suspected Hereditary Spastic Paraplegia with Seven Novel Variants

Annals of Indian Academy of Neurology
Background and Objectives: Hereditary spastic paraplegia (HSP) is a group of neurodegenerative disorders characterized by genetic and clinical diversity.
Taha Reşid Özdemir, Pınar Gençpınar, Roza Sarıteke, Safa M Dagdas, Senay Haspolat, Bedile I Tiftikcioglu, Nihal Olgaç Dündar, Berk Özyılmaz   +7 more
doaj   +1 more source

Scheimpflug imaging for keratoconus and ectatic disease

Indian Journal of Ophthalmology, 2013
Scheimpflug cross-sectioning anterior segment imaging offers significant advantages over traditional placido based curvature analysis and ultrasound pachymetry. The accurate measurement of both the anterior and posterior corneal surfaces and the anterior
Michael W Belin, Renato Ambrósio
doaj   +1 more source

Common in atherogenesis and carcinogenesis: clonal hematopoiesis

Российский кардиологический журнал, 2023
Clonal hematopoiesis is a common age-dependent state accompanied by the expansion of mutant hematopoietic stem cells as a result of somatic mutations and is associated with a high risk of hematopoietic neoplasms and cardiovascular diseases.
A. A. Sleptsov, M. S. Nazarenko, V. Р. Puzyrev   +2 more
doaj   +1 more source

Heterogeneity of sporadic Parkinson’s disease: molecular approach to solving the problem

Анналы клинической и экспериментальной неврологии, 2007
We performed search for mutations in the LRRK2, PRKN (parkin)and SNCA (a-synuclein) genes in 359 patients of Slavonic ethnicorigin (169 men and 190 women) with Parkinsons disease, ofwhom 345 represented sporadic cases. Age at the disease onset wasfrom 23
S. N. Illarioshkin, P. A. Slominsky, M. I. Shadrina, G. Kh. Bagyeva, T. B. Zagorovskaya, E. D. Markova, A. V. Karabanov, V. V. Poleshchuk, E. V. Polevaya, N. V. Fedorova, S. A. Limborskaya, I. A. Ivanova-Smolenskaya   +11 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Newer protocols and future in collagen cross-linking

Indian Journal of Ophthalmology, 2013
Corneal Cross-Linking (CXL) is an established surgical procedure for the treatment of corneal disorders such as corneal ectasia and keratoconus. This method of treatment stabilises the corneal structure and increases rigidity, reducing the requirement ...
Arthur B Cummings, Rebecca McQuaid, Michael Mrochen   +2 more
doaj   +1 more source

Genetic heterogeneity of murine coronaviruses [PDF]

Archives of Virology, 1983
Several mouse hepatitis viruses (MHV) with different pathogenicity were studied by oligonucleotide fingerprinting. Two strains, MHV-K and MHV-D, which were isolated in Japan and, which cause anaplasia and necrosis of bone marrow and diarrhea, respectively, were found to be closely related to MHV-A59, the prototype MHV.
Lai, M. M. C., Fleming, J. O., Stohlman, St. A., Fujiwara, K.   +3 more
openaire   +2 more sources